Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- bupivacaine / meloxicam
- conivaptan
Interactions between your drugs
meloxicam conivaptan
Applies to: bupivacaine / meloxicam, conivaptan
Coadministration with potent or moderate CYP450 3A4 inhibitors may increase the plasma concentration of meloxicam. In vitro studies indicate that meloxicam is primarily metabolized by CYP450 2C9 with a minor contribution from CYP450 3A4. Clinical studies relating to this interaction are unavailable. NSAID related side effects and toxicity may occur with this combination.
References (5)
- (2025) "Product Information. Symbravo (meloxicam-rizatriptan)." Axsome Therapeutics, Inc.
- (2025) "Product Information. Meloxicam (meloxicam)." Lupin Pharmaceuticals Inc
- (2024) "Product Information. Meloxicam (meloxicam)." Flamingo Pharma (UK) Ltd
- (2017) "Product Information. Meloxicam (meloxicam)." Teva Canada Limited
- (2024) "Product Information. Meloxicam (WGR) (meloxicam)." GM Pharma International Pty Ltd
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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