Drug Interaction Report

Irbesartan may reduce the effects of angiotensin II. Blood pressure should be closely monitored during treatment with angiotensin II, and the dosage adjusted as needed.

If you are taking irbesartan you should avoid potassium-containing salt substitutes or over-the-counter potassium supplements without first talking to your doctor. This can cause high levels of potassium in your blood. High levels of potassium can cause weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs. Call your doctor at once if you have any of these symptoms.