Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- Evac-Q-Kwik (bisacodyl / magnesium citrate)
- magnesium hydroxide
Interactions between your drugs
magnesium hydroxide magnesium citrate
Applies to: magnesium hydroxide, Evac-Q-Kwik (bisacodyl / magnesium citrate)
MONITOR: The concomitant administration of magnesium salts with other magnesium-containing preparations such as antacids or laxatives may increase the risk of magnesium toxicity, particularly in the presence of renal insufficiency. Magnesium toxicity may result in respiratory depression, neuromuscular depression, and heart block.
MANAGEMENT: Clinical and laboratory monitoring for signs of hypermagnesemia and magnesium toxicity is advisable, especially in high-risk patients (e.g., elderly or renally impaired patients).
References (1)
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
magnesium hydroxide bisacodyl
Applies to: magnesium hydroxide, Evac-Q-Kwik (bisacodyl / magnesium citrate)
ADJUST DOSING INTERVAL: By increasing gastric pH, antacids may reduce the resistance of the enteric coating of bisacodyl tablets, resulting in earlier release of bisacodyl and gastric irritation and dyspepsia.
MANAGEMENT: The administration of antacids and bisacodyl should be separated by at least one hour.
References (1)
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Osmotic laxatives
Therapeutic duplication
The recommended maximum number of medicines in the 'osmotic laxatives' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'osmotic laxatives' category:
- Evac-Q-Kwik (bisacodyl / magnesium citrate)
- magnesium hydroxide
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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