Drug Interaction Report

Information for this minor interaction is available on the professional version.

Psyllium may interact with other medications if given at the same time. This can cause your other medications to become less effective. In general, all oral medications should be administered at least 2 hours before or 2 hours after dosing of psyllium. Take psyllium with a full glass (at least 8 ounces) of cool water or another liquid. Taking psyllium without enough liquid may cause it to swell in the throat and cause choking.

Taking linaclotide with food may increase gastrointestinal side effects such as diarrhea, abdominal pain, and gas. The absorption of any other oral medication you may take can be affected if you develop frequent or severe diarrhea. To reduce the risk of gastrointestinal intolerance, linaclotide should be taken on an empty stomach at least 30 minutes prior to the first meal of the day. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.