Drug Interaction Report

Rufinamide may reduce the blood levels of rilpivirine in some patients, which may make the medication less effective. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food can enhance the levels of rufinamide in your body. To ensure maximal oral absorption, rufinamide should be administered with or immediately after a meal. This will make it easier for your body to absorb the medication. Do not drink alcohol while you are taking rufinamide. Alcohol can increase some of the side effects including drowsiness or dizziness. Talk to your doctor or pharmacist if you have any questions or concerns.

Food significantly increases the absorption of rilpivirine. You should take each dose of rilpivirine with a meal. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Grapefruit juice can also increase the absorption of rilpivirine and should preferably be avoided.