Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- valdecoxib
- Xermelo (telotristat)
Interactions between your drugs
valdecoxib telotristat ethyl
Applies to: valdecoxib, Xermelo (telotristat)
Telotristat ethyl may reduce the blood levels and effects of valdecoxib. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
telotristat ethyl food
Applies to: Xermelo (telotristat)
Food increases the absorption of telotristat ethyl. To ensure adequate blood levels of the medication, telotristat ethyl should be administered with food or a meal.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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