Drug Interaction Report

Donepezil can occasionally cause slowing of the heart rate or other irregular heart rhythm, and combining it with medications like apomorphine may increase that risk. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Contact your doctor if you develop dizziness, lightheadedness, fainting, shortness of breath, chest pain, or heart palpitations during treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Information for this minor interaction is available on the professional version.

Alcohol can lower your blood pressure and add to the effects of apomorphine. Drinking alcohol while taking apomorphine may decrease your blood pressure and cause drowsiness. This can cause nausea, extreme drowsiness, slow heartbeat, headaches, and dizziness. If you take apomorphine with alcohol tell your doctor if you have any of these symptoms. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.