Drug Interaction Report

Aminolevulinic acid topical causes your skin to be more sensitive to light in areas where it has been applied. The risk and/or severity of reactions such as redness, scaling, swelling, stinging, and burning may be increased when it is used with other drugs that can also increase sensitivity to light such as verteporfin. You should avoid exposure to sunlight or bright indoor lights (examination lamps, operating room lamps, tanning beds, lights at close proximity) during and for 48 hours after treatment as directed by your doctor. Since sunscreens will not protect you against photosensitivity reactions associated with aminolevulinic acid topical, you should protect treated areas by wearing a wide-brimmed hat or other protective apparel if exposure to sunlight or other intense lights cannot be avoided. Be advised to reduce your light exposure if you experience sensations of stinging and/or burning. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

The recommended maximum number of medicines in the 'photochemotherapeutic agents' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'photochemotherapeutic agents' category:

• aminolevulinic acid topical
• Visudyne (verteporfin)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.