Drug Interaction Report

Omadacycline and magnesium chloride should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of omadacycline into the bloodstream and reduce its effectiveness. If possible, it may be best to avoid taking magnesium chloride while your are being treated with omadacycline. Otherwise, you should separate dosing by 2 to 4 hours, omadacycline should be taken at least 2 hours before and not less than 6 hours after Suprep Bowel Prep (magnesium/potassium/sodium sulfates), or omadacycline and magnesium chloride should be taken as directed by your healthcare provider. Talk to your healthcare provider if you are unsure whether your medications contain something that could potentially interact or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Do not take iron supplements, multivitamins, calcium supplements, or antacids within 4 hours before or after taking omadacycline. These products can make omadacycline less effective in treating your infection. Omadacycline should be taken at least 2 hours before (4 hours for dairy products) or 4 hours after meals. Dairy products can make it harder for your body to absorb the medication.