Drug Interaction Report

Ibuprofen can affect kidney function and may increase the blood levels and effects of oxaliplatin when used together. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience severe nausea and vomiting, diarrhea, fever, chills, body aches, flu-like symptoms, easy bruising or bleeding, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ask your doctor before using ibuprofen together with ethanol (alcohol). Do not drink alcohol while taking ibuprofen. Alcohol can increase your risk of stomach bleeding caused by ibuprofen. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.