Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- alosetron
- Entereg (alvimopan)
Interactions between your drugs
No drug ⬌ drug interactions were found between the drugs in your list. However, this does not necessarily mean no drug interactions exist. Always consult your healthcare provider.
Drug and food interactions
alvimopan food
Applies to: Entereg (alvimopan)
Coadministration with a high-fat meal may decrease the rate and extent of alvimopan absorption. According to the product labeling, alvimopan peak plasma concentration (Cmax) and systemic exposure (AUC) were decreased by approximately 38% and 21%, respectively, and the time to reach peak plasma concentration (Tmax) was prolonged by approximately 1 hour when taken with a high-fat meal. The clinical significance is unknown. In postoperative ileus clinical trials, the preoperative dose of alvimopan was administered in a fasting state, and subsequent doses were given without regard to meals.
References (1)
- (2008) "Product Information. Entereg (alvimopan)." GlaxoSmithKline
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Report options
- Switch to consumer interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Xifaxan
Xifaxan (rifaximin) is used to treat travelers' diarrhea, irritable bowel syndrome with diarrhea ...
Viberzi
Viberzi (eluxadoline) is used to treat irritable bowel Syndrome with Diarrhea (IBS-D). Includes ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Lotronex
Lotronex is used to treat severe, chronic irritable bowel syndrome (IBS) in women. Learn about side ...
EnteraGam
EnteraGam is a medical food indicated for the clinical dietary management of enteropathy (bowel ...
Pepto-Bismol
Pepto-Bismol is antacid used to treat heart burn, indigestion, diarrhea, gas or an upset stomach ...
Imodium A-D
Imodium A-D is used to treat and control diarrhea, including traveler's diarrhea. Learn about side ...
Kaopectate
Kaopectate is used for diarrhea, diarrhea, acute, diarrhea, chronic, helicobacter pylori infection ...
Diamode
Diamode is used for diarrhea, diarrhea, acute, diarrhea, chronic, irritable bowel syndrome ...
Imodium Multi-Symptom Relief
Imodium Multi-Symptom Relief is used for diarrhea, acute
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.