Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- Heparin Sodium (heparin)
- ticlopidine
Interactions between your drugs
heparin ticlopidine
Applies to: Heparin Sodium (heparin), ticlopidine
MONITOR: Although therapy with heparin and ticlopidine often overlaps in clinical practice, the potential for additive anticoagulant effects and increased risk of bleeding should be considered.
MANAGEMENT: The manufacturer recommends that heparin be discontinued before initiating ticlopidine therapy. Patients who are to receive these drugs concomitantly should be closely monitored for signs of bleeding. Clinical trials have reported the concomitant use of heparin and ticlopidine in patients undergoing coronary stenting.
References (1)
- (2001) "Product Information. Ticlid (ticlopidine)." Syntex Laboratories Inc
Drug and food interactions
ticlopidine food
Applies to: ticlopidine
ADJUST DOSING INTERVAL: The bioavailability and gastrointestinal tolerance of ticlopidine is enhanced by food.
MANAGEMENT: Patients may be advised to take ticlopidine with meals.
References (1)
- (2001) "Product Information. Ticlid (ticlopidine)." Syntex Laboratories Inc
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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