Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- aldesleukin
- Hydeltrasol (prednisolone)
Interactions between your drugs
prednisoLONE aldesleukin
Applies to: Hydeltrasol (prednisolone), aldesleukin
GENERALLY AVOID: Glucocorticoids may antagonize the immunoregulatory properties of aldesleukin and reduce its antitumor effectiveness.
MANAGEMENT: Although glucocorticoids can attenuate aldesleukin-induced side effects including fever, renal insufficiency, hyperbilirubinemia, confusion and dyspnea, concomitant administration of these agents with aldesleukin should generally be avoided. However, patients who develop life-threatening signs or symptoms may be treated with dexamethasone until toxicity resolves to an acceptable level.
References (1)
- (2001) "Product Information. Proleukin (aldesleukin)." Chiron Therapeutics
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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