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Drug Interaction Report

This report displays the potential drug interactions for the following 3 drugs:

  • estradiol
  • norgestrel
  • clomiphene

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Interactions between your drugs

No interactions were found between your selected drugs. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Drug and food interactions

Moderate

norgestrel food

Applies to: norgestrel

Grapefruit juice may increase the blood levels of certain medications such as norgestrel. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with norgestrel. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

Switch to professional interaction data

Minor

estradiol food

Applies to: estradiol

Information for this minor interaction is only available at a professional reading level.

For clinical details see professional interaction data.

Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Female hormones

Therapeutic duplication

The recommended maximum number of medicines in the 'female hormones' category to be taken concurrently is usually two. Your list includes three medicines belonging to the 'female hormones' category:

  • estradiol
  • norgestrel
  • clomiphene

Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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