Skip to Content

Septra (sulfamethoxazole / trimethoprim) and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with Septra (sulfamethoxazole / trimethoprim):


trimethoprim Alcohol (Ethanol)

Moderate Drug Interaction

Ask your doctor before using trimethoprim together with ethanol. Do not drink alcohol while you are taking trimethoprim. You may have unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Check your food and medicine labels to be sure these products do not contain alcohol. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Septra (sulfamethoxazole / trimethoprim) drug interactions

There are 373 drug interactions with Septra (sulfamethoxazole / trimethoprim)

Septra (sulfamethoxazole / trimethoprim) disease interactions

There are 12 disease interactions with Septra (sulfamethoxazole / trimethoprim) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.