Pomalyst and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Pomalyst (pomalidomide).
Pomalidomide Food/Lifestyle
Moderate Food Interaction
MONITOR: Cigarette smoking may reduce pomalidomide exposure due to induction of CYP450 1A2, the isoenzyme that is responsible for the metabolic clearance of pomalidomide along with CYP450 3A4.
MANAGEMENT: Patients should be advised that smoking may reduce the efficacy of pomalidomide therapy. Pomalidomide should be taken on an empty stomach, at least 2 hours before or 2 hours after a meal.
References (1)
- (2013) "Product Information. Pomalyst (pomalidomide)." QLT Phototherapeutics Inc
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Pomalyst drug interactions
There are 399 drug interactions with Pomalyst (pomalidomide).
Pomalyst disease interactions
There are 7 disease interactions with Pomalyst (pomalidomide) which include:
- thromboembolism
- hematologic toxicities
- hepatic impairment
- neuropathy
- renal impairment
- smoking
- tumor lysis syndrome
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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