Interferon alfa-2b / ribavirin and Alcohol / Food Interactions
There is 1 alcohol/food/lifestyle interaction with interferon alfa-2b / ribavirin:
ribavirin ↔ food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: Food enhances the oral absorption and bioavailability of ribavirin. Administration of a single oral dose of ribavirin following a high-fat meal delayed absorption (Tmax was doubled) but increased the mean peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) by up to 70% compared to administration in the fasting state.
MANAGEMENT: To ensure maximal oral absorption, ribavirin should be administered with or immediately after a meal.
- "Product Information. Copegus (ribavirin)." Roche Laboratories, Nutley, NJ.
- "Product Information. Rebetol (ribavirin)." Schering-Plough Corporation, Kenilworth, NJ.
interferon alfa-2b / ribavirin drug Interactions
There are 239 drug interactions with interferon alfa-2b / ribavirin
interferon alfa-2b / ribavirin disease Interactions
There are 14 disease interactions with interferon alfa-2b / ribavirin which include:
- Renal Dysfunction
- Autoimmune Diseases
- Hepatic Dysfunction
- Cardiac Disease
- Cns Dysfunction
- Thyroid Dysfunction
- Pulmonary Deterioration
- Renal Dysfunction
- Diabetes Mellitus
- Peripheral Neuropathy
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
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