Mavyret and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Mavyret (glecaprevir / pibrentasvir).
Moderate Food Interaction
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: Food enhances the oral bioavailability of glecaprevir and pibrentasvir. Relative to fasting conditions, mean glecaprevir systemic exposure (AUC) increased by 83% to 163% and mean pibrentasvir AUC increased by 40% to 53% when administered with moderate to high fat meals.
MANAGEMENT: Glecaprevir-pibrentasvir should be administered with food.
- "Product Information. Mavyret (glecaprevir-pibrentasvir)." Abbott Pharmaceutical (2017):
Mavyret drug interactions
There are 171 drug interactions with Mavyret (glecaprevir / pibrentasvir).
Mavyret disease interactions
There are 2 disease interactions with Mavyret (glecaprevir / pibrentasvir) which include:
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Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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