Trecator-SC and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Trecator-SC (ethionamide).
Ethionamide Alcohol (Ethanol)
Major Drug Interaction
GENERALLY AVOID: The concomitant use of protionamide with alcohol may enhance the central nervous system exciting effect of protionamide. The mechanism is not known. Excessive use of alcohol with another thiocarbamide derivative ethionamide, has been reported to precipitate a psychotic reaction. In addition, alcohol tolerance is reported to be reduced during protionamide treatment.
MANAGEMENT: Consumption of alcohol during protionamide treatment should be avoided. The manufacturer of ethionamide also advises that excess alcohol consumption should be avoided during ethionamide therapy (US).
References (2)
- (2001) "Product Information. Trecator-SC (ethionamide)." Wyeth-Ayerst Laboratories
- World Health Organization (2020) WHO Public Assessment Reports (WHOPARs) https://extranet.who.int/pqweb/medicines/prequalification-reports/whopars
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Trecator-SC drug interactions
There are 174 drug interactions with Trecator-SC (ethionamide).
Trecator-SC disease interactions
There are 4 disease interactions with Trecator-SC (ethionamide) which include:
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More about Trecator-SC (ethionamide)
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- During pregnancy
- Drug class: nicotinic acid derivatives
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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