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Donepezil/memantine and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with donepezil / memantine.

Minor

Nicotine Memantine

Minor Drug Interaction

Theoretically, the concomitant administration of memantine and other drugs that undergo active renal tubular secretion may result in altered plasma levels of both drugs. The clinical significance is unknown. When hydrochlorothiazide/triamterene and memantine were coadministered in a clinical study, the bioavailability of hydrochlorothiazide decreased by 20% and there was no change in memantine or triamterene bioavailability.

References (1)
  1. (2003) "Product Information. Namenda (memantine)." Forest Pharmaceuticals

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Donepezil/memantine drug interactions

There are 562 drug interactions with donepezil / memantine.

Donepezil/memantine disease interactions

There are 10 disease interactions with donepezil / memantine which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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