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Donepezil / Memantine Dosage

Medically reviewed by Last updated on Oct 31, 2023.

Applies to the following strengths: 10 mg-7 mg; 10 mg-14 mg; 10 mg-21 mg; 10 mg-28 mg

Usual Adult Dose for Alzheimer's Disease

Patients stabilized on memantine (10 mg twice a day or 28 mg ER once a day) and donepezil 10 mg once a day:

Comments: This drug should be initiated the day following the last dose of memantine and donepezil administered separately.

Treatment of moderate to severe dementia of the Alzheimer's type in patients stabilized on

Renal Dose Adjustments

Liver Dose Adjustments


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:

Storage requirements: Keep this drug in a tight, light-resistant container.




Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.