Darbepoetin alfa and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with darbepoetin alfa.
Darbepoetin Alfa High Blood Pressure (Hypertension)
Major Potential Hazard, Moderate plausibility
erythropoiesis-stimulating agents - hypertension
The use of erythropoiesis-stimulating agents is contraindicated in patients with uncontrolled hypertension. These agents may cause blood pressure to rise. Hypertensive encephalopathy and seizures have been observed in patients with chronic renal failure treated with these agents. Blood pressure should be adequately controlled prior to initiation of therapy, and monitored closely during treatment. Aggressive antihypertensive measures may be necessary, particularly early on in treatment when the hematocrit is increasing. It is recommended to reduce or withhold the use of these agents if blood pressure becomes difficult to control.
Darbepoetin alfa drug interactions
There are 21 drug interactions with darbepoetin alfa.
Darbepoetin alfa disease interactions
There are 4 disease interactions with darbepoetin alfa which include:
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- Drug class: recombinant human erythropoietins
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
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