Crizotinib and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with crizotinib.
Crizotinib Food
Major Food Interaction
Do not consume grapefruit or grapefruit juice during treatment with crizotinib unless directed otherwise by your doctor. Grapefruit juice can increase the blood levels of crizotinib to dangerous levels and cause an irregular heart rhythm that may be serious. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats during treatment with crizotinib. You may take crizotinib with or without food, but take it the same time each day. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
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Crizotinib drug interactions
There are 809 drug interactions with crizotinib.
Crizotinib disease interactions
There are 7 disease interactions with crizotinib which include:
- bradycardia
- gastrointestinal perforation
- hepatic impairment
- ILD/pneumonitis
- QT prolongation
- renal impairment
- visual loss
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More about crizotinib
- crizotinib consumer information
- Check interactions
- Compare alternatives
- Reviews (8)
- Side effects
- Dosage information
- During pregnancy
- Drug class: multikinase inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
