Xalkori and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Xalkori (crizotinib).
Crizotinib Food
Major Food Interaction
Do not consume grapefruit or grapefruit juice during treatment with crizotinib unless directed otherwise by your doctor. Grapefruit juice can increase the blood levels of crizotinib to dangerous levels and cause an irregular heart rhythm that may be serious. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats during treatment with crizotinib. You may take crizotinib with or without food, but take it the same time each day. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Xalkori drug interactions
There are 771 drug interactions with Xalkori (crizotinib).
Xalkori disease interactions
There are 7 disease interactions with Xalkori (crizotinib) which include:
- bradycardia
- gastrointestinal perforation
- hepatic impairment
- ILD/pneumonitis
- QT prolongation
- renal impairment
- visual loss
More about Xalkori (crizotinib)
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- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: multikinase inhibitors
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.