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Xalkori (crizotinib) Drug Interactions

A total of 740 drugs are known to interact with Xalkori (crizotinib).

  • 328 major drug interactions
  • 395 moderate drug interactions
  • 17 minor drug interactions

Show all medications in the database that may interact with Xalkori (crizotinib).

Check for interactions

Type in a drug name to check for interactions with Xalkori (crizotinib).

Most frequently checked interactions

View interaction reports for Xalkori (crizotinib) and the medicines listed below.

  • Alecensa (alectinib)
  • Amaryl (glimepiride)
  • Celexa (citalopram)
  • cetirizine (Zyrtec, Equate Allergy Relief, Aller-Tec, All Day Allergy, All Day Allergy Children's, Aller-Tec Children's, PediaCare Children's 24-Hour Allergy, Children's Allergy Relief, Zyrtec Hives, Children's Zyrtec, Alleroff)
  • Compazine (prochlorperazine)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • grapefruit
  • hydrocodone (Hysingla ER, Zohydro ER, Vantrela ER)
  • ibuprofen (Advil, Motrin, IBU, Children's Motrin, Proprinal, Advil Liqui-Gels, Ibu-8, Motrin IB, Motrin Childrens, Rufen, Childrens Ibuprofen Berry, IBU-200, Ibuprofen PMR, Advil Migraine, Ibu-Tab, Genpril, Menadol, Advil Children's, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Addaprin, Motrin Infant Drops, NeoProfen, Caldolor, Motrin Pediatric, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • Lasix (furosemide)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Euthyrox, Unithroid, Levothyrox, Eutroxsig, Levo-T, Oroxine, L Thyroxine Roche, Levotabs, Novothyrox, Tirosint-Sol, Levotec, Evotrox)
  • lorazepam (Ativan, Lorazepam Intensol)
  • Neurontin (gabapentin)
  • ondansetron (Zofran, Zofran ODT, Zuplenz)
  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, RoxyBond, Percolone, Oxecta, Oxydose, Oxyfast, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol, Dazidox)
  • pantoprazole (Protonix, Protonix IV)
  • Toradol (ketorolac)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, ConZip, Zydol, Tramal SR, GenRx Tramadol, Zamadol, Ryzolt, Tramedo, Larapam SR, Tramahexal SR, Tramahexal, Zydol XL, Rybix ODT, Ultram ODT)
  • Vitamin B12 (cyanocobalamin)
  • Xanax (alprazolam)
  • Zofran (ondansetron)
  • Zykadia (ceritinib)

Xalkori (crizotinib) alcohol/food interactions

There is 1 alcohol/food interaction with Xalkori (crizotinib)

Xalkori (crizotinib) disease interactions

There are 5 disease interactions with Xalkori (crizotinib) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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