Cladribine and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with cladribine.
Cladribine Food/Lifestyle
Moderate Food Interaction
ADJUST DOSING INTERVAL: Oral cladribine may increase the bioavailability of other drugs, which may increase the risk or severity of adverse reactions. Cladribine tablets may contain hydroxypropyl betadex, which could form a complex with the active ingredients of other drugs, especially agents with low solubility. The clinical relevance of this interaction remains unknown.
MANAGEMENT: Administration of oral cladribine should be separated from any other oral drug by at least 3 hours.
References (3)
- (2001) "Product Information. Leustatin (cladribine)." Ortho Biotech Inc
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
- Cerner Multum, Inc. "Australian Product Information."
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Cladribine drug interactions
There are 502 drug interactions with cladribine.
Cladribine disease interactions
There are 5 disease interactions with cladribine which include:
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- During pregnancy
- Drug class: antimetabolites
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
