Alvimopan and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with alvimopan.
Alvimopan Food
Minor Food Interaction
Coadministration with a high-fat meal may decrease the rate and extent of alvimopan absorption. According to the product labeling, alvimopan peak plasma concentration (Cmax) and systemic exposure (AUC) were decreased by approximately 38% and 21%, respectively, and the time to reach peak plasma concentration (Tmax) was prolonged by approximately 1 hour when taken with a high-fat meal. The clinical significance is unknown. In postoperative ileus clinical trials, the preoperative dose of alvimopan was administered in a fasting state, and subsequent doses were given without regard to meals.
References (1)
- (2008) "Product Information. Entereg (alvimopan)." GlaxoSmithKline
Switch to consumer interaction data
Alvimopan drug interactions
There are 41 drug interactions with alvimopan.
Alvimopan disease interactions
There is 1 disease interaction with alvimopan which include:
Report options
More about alvimopan
- alvimopan consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: peripheral opioid receptor antagonists
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Lidoderm
Lidoderm is a lidocaine patch used to relieve nerve pain after shingles by numbing the skin and ...
Xylocaine Jelly
Xylocaine Jelly is used for anal itching, anesthesia, burns, external, gastrointestinal surgery ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Entereg
Entereg (alvimopan) is used to speed recovery of stomach and intestinal functions after a ...
Lidocaine topical
Lidocaine topical is used for anal itching, anesthesia, burns, external, gastrointestinal surgery ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
