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Alvimopan Side Effects

Medically reviewed by Drugs.com. Last updated on Sep 19, 2023.

Applies to alvimopan: oral capsule.

Warning

Oral route (Capsule)

There was a greater incidence of myocardial infarction in alvimopan-treated patients compared to placebo-treated patients in a 12-month clinical trial, although a causal relationship has not been established. In short-term trials with Alvimopan, no increased risk of myocardial infarction was observed. Because of the potential risk of myocardial infarction with long-term use, alvimopan is available only through a restricted program for short-term use (15 doses) under a Risk Evaluation and Mitigation Strategy (REMS) called the Alvimopan REMS Program.

Serious side effects of Alvimopan

Along with its needed effects, alvimopan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking alvimopan:

More common

Less common

Other side effects of Alvimopan

Some side effects of alvimopan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

For Healthcare Professionals

Applies to alvimopan: oral capsule.

General

The most commonly reported side effect included dyspepsia.[Ref]

Gastrointestinal

Common (1% to 10%): Dyspepsia[Ref]

Frequently asked questions

References

1. Product Information. Entereg (alvimopan). GlaxoSmithKline. 2008.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.