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Sulfatrim (sulfamethoxazole / trimethoprim) Drug Interactions

A total of 495 drugs are known to interact with Sulfatrim (sulfamethoxazole / trimethoprim).

  • 112 major drug interactions
  • 165 moderate drug interactions
  • 218 minor drug interactions

Show all medications in the database that may interact with Sulfatrim (sulfamethoxazole / trimethoprim).

Check for interactions with Sulfatrim (sulfamethoxazole / trimethoprim)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Sulfatrim (sulfamethoxazole / trimethoprim)

  • Advil (ibuprofen)
  • albuterol (ProAir HFA, Ventolin, Ventolin HFA, Proventil, Proventil HFA, Respirol, ProAir RespiClick, AccuNeb, Airet, Volmax, Vospire ER)
  • amlodipine (Norvasc)
  • amoxicillin (Amoxil, Trimox, Apo-Amoxi, Moxatag, Moxilin, Amoxicot, DisperMox, Wymox, Biomox)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Arthritis Pain, Fasprin, Ecotrin Adult Low Strength, Low Dose ASA, Bufferin, Aspiritab, Aspirin Lite Coat, Easprin, Bayer Children's Aspirin, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Bayer Aspirin Regimen, Aspirtab, Halfprin, Aspergum, Durlaza, Acuprin 81, Miniprin, Bufferin Low Dose, Empirin, Buffered Aspirin, Entercote, St. Joseph Aspirin, Ascriptin Enteric, Ecpirin, Bayer Women's Aspirin With Calcium, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Aspi-Cor, Medi-Seltzer, Sloprin, St. Joseph 81 mg Chewable Aspirin, ZORprin, Bayer Aspirin Extra Strength Plus, Buffex, Ecotrin Maximum Strength, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Zero-Order Release, YSP Aspirin, Migralex, Heartline, Bayer Advanced Aspirin, Buffasal)
  • atorvastatin (Lipitor)
  • azithromycin (Zithromax, Azithromycin Dose Pack, Z-Pak, Zmax)
  • ciprofloxacin (Cipro, Cipro Cystitis Pack, Cipro XR, Cipro I.V., Proquin XR)
  • Control (phenylpropanolamine)
  • furosemide (Lasix, Diaqua-2, Lo-Aqua)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • hydrochlorothiazide (Microzide, HydroDIURIL, Esidrix, Diaqua, Aquazide H, Oretic, Carozide, Hydro Par, Ezide, Loqua)
  • ibuprofen (Advil, Motrin, IBU, Proprinal, Advil Liqui-Gels, Motrin IB, IBU-200, Nuprin, Advil Infant's Concentrated Drops, Children's Motrin, Advil Children's, Ibu-8, Ibuprofen PMR, Caldolor, Motrin Childrens, Motrin Migraine Pain, Addaprin, Ibu-4, Ibu-Tab, Rufen, Midol IB, A-G Profen, Childrens Ibuprofen Berry, Advil Migraine, Ibu-6, Motrin Infant Drops, NeoProfen, Genpril, Haltran, Menadol, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • levofloxacin (Levaquin, Levaquin Leva-Pak)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • metformin (Glucophage, Glumetza, Glucophage XR, Riomet, Fortamet)
  • metronidazole (Flagyl, Flagyl IV, Metro, Metro IV, Flagyl 375, Flagyl ER, Protostat, Metryl)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • pantoprazole (Protonix, Protonix IV)
  • prednisone (Deltasone, Rayos, Sterapred DS, Sterapred, Prednicot, Meticorten, Liquid Pred, Orasone, Prednicen-M)
  • Septra (sulfamethoxazole / trimethoprim)
  • spironolactone (Aldactone, CaroSpir)
  • Tylenol (acetaminophen)
  • Vitamin C (ascorbic acid)
  • Vitamin D3 (cholecalciferol)

Sulfatrim (sulfamethoxazole / trimethoprim) alcohol/food Interactions

There is 1 alcohol/food interaction with Sulfatrim (sulfamethoxazole / trimethoprim)

Sulfatrim (sulfamethoxazole / trimethoprim) disease Interactions

There are 12 disease interactions with Sulfatrim (sulfamethoxazole / trimethoprim) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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