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Septra IV (sulfamethoxazole / trimethoprim) Drug Interactions

A total of 497 drugs are known to interact with Septra IV (sulfamethoxazole / trimethoprim).

  • 112 major drug interactions
  • 166 moderate drug interactions
  • 219 minor drug interactions

Show all medications in the database that may interact with Septra IV (sulfamethoxazole / trimethoprim).

Check for interactions with Septra IV (sulfamethoxazole / trimethoprim)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Septra IV (sulfamethoxazole / trimethoprim)

  • amphotericin b liposomal (AmBisome)
  • calcium carbonate (Caltrate, Tums Regular Strength, Oyster Shell Calcium 500, Os-Cal, Calcarb, Tums Ultra 1000, Oysco 500, Oyster, Trial Antacid, Calcium Concentrate, Tums Kids, Tums Chewy Bites, Oyst Cal 500, Oyster Shell, Oyster Calcium, Oyster Cal, Pepto Children's, Calcid, Tums Smoothies, Nephro Calci, Amitone, Calcitab, Alka-Seltzer Fruit Chews (Antacid), Oyst Cal, Calcium Liquid Softgel, Maalox Children's Relief, D-Cal, Tums Sugar-Free, Rolaids Extra Strength Softchews, Tums Chewy Delights, Alcalak, Cal-Mint, Alka-Seltzer Heartburn ReliefChews, Maalox Quick Dissolve Extra Strength, Calci-Chew, Calci Mix, Dicarbosil, Equilet, Chooz, Tums Extra Strength 750, Alkets, Titralac, Oyster Cal 500, Super Calcium, Caltro, Cal Oys, Alkums, Cal-Gest, Alka-Mints, Ami-Lac, Calcium Oyster, Mylanta Child, Ultra Mylanta Calci Tabs, Extra Strength Mylanta Calci Tabs, Surpass, Surpass Extra Strength, Icar Prenatal Chewable Calcium, Calcium Oyster Shell, Maalox Regular Strength, Tums Freshers)
  • clemastine (Tavist, Dayhist-1, 12 Hour Allergy Relief, Leader Allerhist, Allerhist-1, Tavist-1, Dailyhist-1, Contac 12 Hour Allergy, Tavist Allergy, Dayhist Allergy)
  • clonidine (Catapres, Kapvay, Clonidine ER, Catapres-TTS, Duraclon, Nexiclon XR, Jenloga)
  • Coenzyme Q10 (ubiquinone)
  • cyclosporine (Neoral, Sandimmune, Gengraf)
  • enalapril (Vasotec, Epaned)
  • furosemide (Lasix, Diaqua-2, Lo-Aqua)
  • L-Carnitine (levocarnitine)
  • levetiracetam (Keppra, Keppra XR, Roweepra, Spritam, Roweepra XR, Elepsia XR)
  • methylprednisolone (Medrol Dosepak, Medrol, MethylPREDNISolone Dose Pack, Solu-Medrol, Depo-Medrol, Methylpred DP, A-Methapred, Duralone, Adlone-80, M-Prednisolone, Methacort 40, Depopred, Dep Medalone 80, Depoject-80, Adlone-40, Depmedalone, Medipred, Medralone, Medralone 40, Medralone 80, Methylcotol, Predacorten, Med-Jec-40, Methacort 80, Methylcotolone)
  • morphine (MS Contin, Morphine Sulfate ER, Roxanol, Morphine Sulfate IR, Kadian, MSIR, MorphaBond ER, Morphine Sulfate SR, Duramorph, Avinza, Morphine LP Epidural, Oramorph SR, Arymo ER, Statex, Astramorph PF, Mitigo, Morphine Rapi-Ject, Roxanol-T, RMS, Infumorph, Duramorph PF, OMS, Roxanol 100, Rescudose, MS/S, Doloral, Doloral Sirop, M-Eslon, Morphitec, M O S)
  • mycophenolate mofetil (CellCept)
  • nitroprusside (Nitropress, Nipride RTU)
  • nystatin (Mycostatin, Nilstat, Nystat-Rx, Bio-Statin, Mycostatin Pastilles, Nystex)
  • pantoprazole (Protonix, Protonix IV)
  • potassium chloride (Klor-Con, KCl, K-Dur, Klor-Con M20, K-Tab, Klor-Con M10, Micro-K, Kay Ciel, Klor-Con 10, K-Dur 20, Slow-K, K-Lor, Klor-Con Sprinkle, Klotrix, Micro-K 10, Cena K, Klor-Con 8, K-Dur 10, Epiklor, Kaochlor, Kaon-CI, K-Norm, Kal Potassium 99, Kaochlor S-F, Kaon-CL 20%, K-Sol, K + Potassium, Klor-Con/25, K-8, K-10, Glu-K, Kaon-CL 10, Kato, Ed K+10, PC-10, Ten-K, Klor-Con M15, K-Vescent (Potassium Chloride), K+Care, Klorvess, Rum-K, Gen-K)
  • sildenafil (Viagra, Revatio)
  • ursodiol (Actigall, Urso, Urso Forte, Urso DS)
  • Vitamin D3 (cholecalciferol)

Septra IV (sulfamethoxazole / trimethoprim) alcohol/food interactions

There is 1 alcohol/food interaction with Septra IV (sulfamethoxazole / trimethoprim)

Septra IV (sulfamethoxazole / trimethoprim) disease interactions

There are 12 disease interactions with Septra IV (sulfamethoxazole / trimethoprim) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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