Olysio (simeprevir) Drug Interactions
A total of 160 drugs are known to interact with Olysio (simeprevir).
- 84 major drug interactions
- 76 moderate drug interactions
Check for interactions with Olysio (simeprevir)
Common medications checked in combination with Olysio (simeprevir)
- amlodipine (Norvasc)
- Daklinza (daclatasvir)
- Farxiga (dapagliflozin)
- Harvoni (ledipasvir / sofosbuvir)
- hydrochlorothiazide (Microzide, HydroDIURIL, Esidrix, Diaqua, Aquazide H, Oretic, Carozide, Hydro Par, Ezide, Loqua)
- Lipitor (atorvastatin)
- Lotrel (amlodipine / benazepril)
- metformin (Glucophage, Glumetza, Glucophage XR, Riomet, Fortamet)
- Metoprolol Succinate ER (metoprolol)
- Nuvigil (armodafinil)
- omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
- pantoprazole (Protonix, Protonix IV)
- Protonix (pantoprazole)
- RibaPak (ribavirin)
- Sovaldi (sofosbuvir)
- tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Tramedo, GenRx Tramadol, ConZip, Zydol, Ryzolt, Larapam SR, Tramahexal, Zamadol, Tramal SR, Tramahexal SR, Zydol XL, Rybix ODT, Rybix, Ultram ODT)
- trazodone (Desyrel, Oleptro, Desyrel Dividose)
- Truvada (emtricitabine / tenofovir)
- venlafaxine (Effexor, Effexor XR)
- Victoza (liraglutide)
- Vitamin D3 (cholecalciferol)
- warfarin (Coumadin, Jantoven)
Olysio (simeprevir) alcohol/food Interactions
There is 1 alcohol/food interaction with Olysio (simeprevir)
More about Olysio (simeprevir)
- Olysio Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- En Español
- 4 Reviews
- Drug class: protease inhibitors
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No information available. |
Do not stop taking any medications without consulting your healthcare provider.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
