Axtle Interactions
There are 385 drugs known to interact with Axtle (pemetrexed), along with 5 disease interactions. Of the total drug interactions, 50 are major, and 335 are moderate.
- View Axtle disease interactions (5)
Medications known to interact with Axtle
Note: Showing generic names only.
A
- abrocitinib
- acyclovir
- adalimumab
- adefovir
- adenovirus vaccine
- aldesleukin
- alefacept
- alemtuzumab
- allopurinol
- amikacin
- amikacin liposome
- aminosalicylic acid
- amoxicillin
- amphotericin b
- amphotericin b cholesteryl sulfate
- amphotericin b lipid complex
- amphotericin b liposomal
- ampicillin
- anakinra
- anthrax vaccine adsorbed
- aspirin
- atezolizumab
- avelumab
- azathioprine
- aztreonam
B
- bacampicillin
- bacitracin
- balsalazide
- baricitinib
- bcg
- bcg vaccine
- bendamustine
- bifidobacterium infantis
- bifidobacterium longum
- bleomycin
- brewer's yeast
- bromfenac
- busulfan
C
- cabazitaxel
- canakinumab
- candida albicans extract
- capreomycin
- carbenicillin
- carboplatin
- cefaclor
- cefadroxil
- cefamandole
- cefazolin
- cefdinir
- cefditoren
- cefixime
- cefmetazole
- cefonicid
- cefoperazone
- cefotaxime
- cefoxitin
- cefpodoxime
- cefprozil
- ceftizoxime
- cefuroxime
- celecoxib
- cemiplimab
- cephalexin
- cephalothin
- cephapirin
- cephradine
- certolizumab
- chikungunya vaccine, live (cvx 317)
- chikungunya vaccine, recombinant (cvx 329)
- chlorambucil
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- cholera vaccine
- cholera vaccine, live
- choline salicylate
- cidofovir
- cimetidine
- cinoxacin
- ciprofloxacin
- cisplatin
- cladribine
- clofarabine
- cloxacillin
- clozapine
- coccidioidin skin test
- colistimethate
- cosibelimab
- COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Pfizer) vaccine
- creatine
- cyclosporine
- cytarabine
- cytarabine liposomal
D
- dacarbazine
- daunorubicin
- daunorubicin liposomal
- deferasirox
- deferiprone
- delafloxacin
- dengue vaccine
- denosumab
- deucravacitinib
- diclofenac
- dicloxacillin
- diflunisal
- dimethyl fumarate
- diroximel fumarate
- doripenem
- dostarlimab
- durvalumab
- dyphylline
E
- efalizumab
- efbemalenograstim alfa
- eflapegrastim
- elranatamab
- enoxacin
- entecavir
- ertapenem
- etanercept
- etidronate
- etodolac
- etoposide
- etrasimod
F
- famciclovir
- famotidine
- fenoprofen
- filgrastim
- fingolimod
- flecainide
- floxuridine
- fludarabine
- fluorouracil
- flurbiprofen
- foscarnet
G
- gallium nitrate
- ganciclovir
- gatifloxacin
- gemcitabine
- gemifloxacin
- gentamicin
- givosiran
- glucarpidase
- golimumab
H
- haemophilus b conjugate (hboc) vaccine
- haemophilus b conjugate (prp-omp) vaccine
- haemophilus b conjugate (prp-t) vaccine
- hepatitis a adult vaccine
- hepatitis a pediatric vaccine
- hepatitis b adult vaccine
- hepatitis b pediatric vaccine
- histoplasmin
- human papillomavirus vaccine
- hydroxyurea
I
- ibandronate
- ibritumomab
- ibuprofen
- idarubicin
- idelalisib
- ifosfamide
- imatinib
- indomethacin
- infliximab
- influenza virus vaccine, h1n1, inactivated
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, h5n1
- influenza virus vaccine, inactivated
- influenza virus vaccine, live
- inotersen
- interferon alfa-2a
- interferon alfa-2b
- iobenguane I 131
- ipilimumab
- isatuximab
J
K
L
- lactobacillus acidophilus
- lactobacillus reuteri
- lactobacillus rhamnosus
- lactobacillus rhamnosus gg
- leflunomide
- levofloxacin
- lifileucel
- lithium
- lomefloxacin
- lomustine
- loncastuximab tesirine
- loracarbef
- lurbinectedin
- lutetium lu 177 dotatate
- lutetium lu 177 vipivotide tetraxetan
- lyme disease vaccine
M
- magnesium salicylate
- measles virus vaccine
- meclofenamate
- mefenamic acid
- meloxicam
- melphalan
- melphalan flufenamide
- meningococcal conjugate vaccine
- meningococcal group acwy conjugate-group b vaccine (cvx 316)
- meningococcal group B vaccine
- meningococcal polysaccharide vaccine
- mercaptopurine
- meropenem
- mesalamine
- metformin
- methicillin
- methotrexate
- methoxyflurane
- mezlocillin
- midodrine
- mitomycin
- mitoxantrone
- mixed respiratory vaccine
- monomethyl fumarate
- moxetumomab pasudotox
- moxifloxacin
- mumps skin test antigen
- mumps virus vaccine
- mycophenolate mofetil
- mycophenolic acid
N
- nabumetone
- nadofaragene firadenovec
- nafcillin
- nalidixic acid
- naproxen
- natalizumab
- naxitamab
- nelarabine
- neomycin
- netilmicin
- niraparib
- nivolumab
- norfloxacin
O
- ocrelizumab
- ofloxacin
- olaparib
- olsalazine
- omacetaxine
- oseltamivir
- oxacillin
- oxaliplatin
- oxaprozin
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- palifermin
- pamidronate
- pegfilgrastim
- pembrolizumab
- penicillin g benzathine
- penicillin g potassium
- penicillin g sodium
- penicillin v potassium
- pentamidine
- pertussis, acellular
- phenylbutazone
- piperacillin
- piroxicam
- plague vaccine
- plazomicin
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 23-polyvalent vaccine
- pneumococcal 7-valent vaccine
- poliovirus vaccine, inactivated
- poliovirus vaccine, live, trivalent
- polymyxin b
- ponesimod
- pralatrexate
- probenecid
- procainamide
- procaine penicillin
Q
R
- rabies vaccine, human diploid cell
- rabies vaccine, purified chick embryo cell
- radium 223 dichloride
- ranitidine
- ranitidine bismuth citrate
- remdesivir
- retifanlimab
- rilonacept
- ritlecitinib
- rofecoxib
- roflumilast
- ropeginterferon alfa-2b
- rotavirus vaccine
- rsv vaccine pref3, recombinant
- rsv vaccine, mrna
- rsv vaccine, pref a-pref b, recombinant
- rubella virus vaccine
- ruxolitinib
S
- saccharomyces boulardii lyo
- salsalate
- samarium sm 153 lexidronam
- sapropterin
- sargramostim
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- siponimod
- sipuleucel-T
- sirolimus
- skin test antigens, multiple
- smallpox and mpox vaccine
- smallpox vaccine
- sodium phosphate p32
- sodium salicylate
- sodium thiosalicylate
- staphage lysate (spl)
- streptococcus salivarius
- streptomycin
- streptozocin
- strontium-89 chloride
- sulfasalazine
- sulindac
T
- tacrolimus
- tafasitamab
- talimogene laherparepvec
- talquetamab
- tbo-filgrastim
- teclistamab
- telavancin
- temsirolimus
- tenofovir alafenamide
- tenofovir disoproxil
- teriflunomide
- tetanus toxoid
- thalidomide
- thiotepa
- ticarcillin
- tick-borne encephalitis (inactivated) pediatric vaccine
- tick-borne encephalitis (inactivated) vaccine
- tislelizumab
- tobramycin
- tofacitinib
- tolmetin
- topotecan
- toripalimab
- trabectedin
- tremelimumab
- treosulfan
- triamterene
- trichophyton skin test
- trospium
- tuberculin purified protein derivative
- typhoid vaccine, inactivated
- typhoid vaccine, live
U
V
- valacyclovir
- valdecoxib
- valganciclovir
- vancomycin
- varicella virus vaccine
- vinblastine
- vinorelbine
- vitamin e
- voclosporin
Y
Z
Axtle disease interactions
There are 5 disease interactions with Axtle (pemetrexed) which include:
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More about Axtle (pemetrexed)
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- Side effects
- Dosage information
- During pregnancy
- Drug class: antimetabolites
- Breastfeeding
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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