Loperamide/simethicone Drug Interactions
Currently displaying a list of 358 drugs known to interact with loperamide / simethicone.
- 44 major drug interactions
- 313 moderate drug interactions
- 1 minor drug interaction
Medications known to interact with loperamide/simethicone
Note: Showing generic names only.
A
- abarelix
- abiraterone
- abrocitinib
- acrivastine
- adagrasib
- albuterol
- alfuzosin
- amiodarone
- amisulpride
- amitriptyline
- amoxapine
- amprenavir
- anagrelide
- apalutamide
- apomorphine
- apraclonidine ophthalmic
- aripiprazole
- arsenic trioxide
- asciminib
- asenapine
- astemizole
- atazanavir
- atomoxetine
- atropine
- avacopan
- azatadine
- azithromycin
B
- bedaquiline
- belladonna
- benzgalantamine
- benztropine
- bepridil
- berotralstat
- bicalutamide
- biperiden
- boceprevir
- bosutinib
- brexpiprazole
- brigatinib
- brimonidine ophthalmic
- brimonidine topical
- brompheniramine
- buprenorphine
- butorphanol
C
- cabozantinib
- capmatinib
- carbinoxamine
- ceritinib
- cetirizine
- chlorcyclizine
- chloroquine
- chlorpheniramine
- chlorpromazine
- cholestyramine
- cilostazol
- cimetidine
- ciprofloxacin
- cisapride
- citalopram
- clarithromycin
- clemastine
- clidinium
- clofazimine
- clomipramine
- clopidogrel
- clozapine
- cobicistat
- codeine
- conivaptan
- crizotinib
- cyclizine
- cyclobenzaprine
- cyclosporine
- cyproheptadine
D
- daclatasvir
- danicopan
- daridorexant
- darifenacin
- dasatinib
- daunorubicin
- daunorubicin liposomal
- degarelix
- delavirdine
- desipramine
- desmopressin
- deutetrabenazine
- dexbrompheniramine
- dexchlorpheniramine
- dicyclomine
- diltiazem
- dimenhydrinate
- diphenhydramine
- disopyramide
- dofetilide
- dolasetron
- donepezil
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- doxylamine
- dronedarone
- droperidol
E
- efavirenz
- elacestrant
- elagolix
- eliglustat
- eluxadoline
- encorafenib
- entrectinib
- enzalutamide
- epirubicin
- erdafitinib
- eribulin
- erythromycin
- escitalopram
- esketamine
- ethanol
- etrasimod
- ezogabine
F
- fexinidazole
- fidaxomicin
- fingolimod
- flavoxate
- flecainide
- flibanserin
- fluconazole
- fluoxetine
- fluphenazine
- flutamide
- fosamprenavir
- foscarnet
- fostamatinib
- fostemsavir
- futibatinib
G
- galantamine
- gatifloxacin
- gemfibrozil
- gemifloxacin
- gepirone
- gilteritinib
- givinostat
- glasdegib
- glycopyrrolate
- goserelin
- granisetron
- grepafloxacin
H
- halofantrine
- haloperidol
- halothane
- histrelin
- hydrocodone
- hydromorphone
- hydroxychloroquine
- hydroxyzine
- hyoscyamine
I
- ibrutinib
- ibutilide
- idarubicin
- idelalisib
- iloperidone
- imipramine
- indinavir
- inotuzumab ozogamicin
- isavuconazonium
- istradefylline
- itraconazole
- ivacaftor
- ivosidenib
K
L
- lapatinib
- lasmiditan
- lefamulin
- lenacapavir
- lenvatinib
- leuprolide
- levacetylleucine
- levocetirizine
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levorphanol
- levothyroxine
- levothyroxine / liothyronine
- liothyronine
- liotrix
- lisdexamfetamine
- lithium
- lofexidine
- lomefloxacin
- lomitapide
- lonafarnib
- loxapine
M
- macimorelin
- maprotiline
- mavorixafor
- meclizine
- mefloquine
- mepenzolate
- meperidine
- mesoridazine
- methadone
- methdilazine
- methotrimeprazine
- methscopolamine
- metronidazole
- mibefradil
- midostaurin
- mifepristone
- mirtazapine
- mobocertinib
- molindone
- morphine
- morphine liposomal
- moxifloxacin
N
O
- ofloxacin
- olanzapine
- oliceridine
- olodaterol
- olopatadine nasal
- ondansetron
- opium
- orphenadrine
- osilodrostat
- osimertinib
- oxaliplatin
- oxybutynin
- oxycodone
- oxymorphone
- oxytocin
- ozanimod
P
- pacritinib
- paliperidone
- palonosetron
- panobinostat
- papaverine
- pasireotide
- pazopanib
- pemigatinib
- pentamidine
- pentazocine
- perflutren
- perphenazine
- phenindamine
- physostigmine
- pimavanserin
- pimozide
- pirtobrutinib
- pitolisant
- ponatinib
- ponesimod
- posaconazole
- pralsetinib
- pramlintide
- pretomanid
- primaquine
- probucol
- procainamide
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propafenone
- propantheline
- propiomazine
- propofol
- propoxyphene
- protriptyline
- pyrilamine
Q
R
- ranitidine
- ranitidine bismuth citrate
- ranolazine
- relugolix
- revumenib
- ribociclib
- rilpivirine
- ripretinib
- risperidone
- ritonavir
- rivastigmine
- rolapitant
- romidepsin
- rucaparib
S
- saquinavir
- sarecycline
- scopolamine
- selpercatinib
- sertraline
- sevoflurane
- siponimod
- solifenacin
- sorafenib
- sotalol
- sotorasib
- sparfloxacin
- sparsentan
- spironolactone
- sunitinib
T
- tacrine
- tacrolimus
- tamoxifen
- tebentafusp
- telaprevir
- telavancin
- telithromycin
- tepotinib
- terbutaline
- terfenadine
- tetrabenazine
- thiethylperazine
- thioridazine
- thiothixene
- thyroid desiccated
- tipranavir
- tizanidine
- tolterodine
- tolvaptan
- toremifene
- tramadol
- trazodone
- triclabendazole
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimipramine
- tripelennamine
- triprolidine
- triptorelin
- troleandomycin
- trospium
- tucatinib
U
V
- valbenazine
- vandetanib
- vardenafil
- vasopressin
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vibegron
- vimseltinib
- voclosporin
- voriconazole
Z
Loperamide/simethicone alcohol/food interactions
There is 1 alcohol/food interaction with loperamide / simethicone.
Loperamide/simethicone disease interactions
There are 4 disease interactions with loperamide / simethicone which include:
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- During pregnancy
- Drug class: antidiarrheals
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
