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Loperamide / Simethicone Side Effects

Medically reviewed by Drugs.com. Last updated on Mar 29, 2024.

Applies to loperamide / simethicone: oral tablet.

Important warnings This medicine can cause some serious health issues

  • Do not take more than the package label says or your doctor told you to take.

    Taking more than you were told can cause very bad heart problems, including an abnormal heartbeat.

    Sometimes, these heart problems can lead to death.

    Taking this drug with certain other drugs may also raise the chance of heart problems.

    Talk with your doctor.

  • Do not give to a child younger than 2 years of age.

Serious side effects

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

Other side effects

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

For healthcare professionals

Applies to loperamide/simethicone: oral tablet, oral tablet chewable.

Gastrointestinal adverse events

Nervous system

Dermatologic

Other

Hypersensitivity

Genitourinary

Ocular

References

1. (2006) "Product Information. Imodium Advanced (loperamide-simethicone)." Johnson and Johnson/Merck

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Cerner Multum, Inc. "Australian Product Information."

Frequently asked questions

Further information

Loperamide/simethicone side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.