Isoniazid/pyrazinamide/rifampin Drug Interactions
Currently displaying a list of 942 drugs known to interact with isoniazid / pyrazinamide / rifampin.
- 301 major drug interactions
- 616 moderate drug interactions
- 25 minor drug interactions
Medications known to interact with isoniazid/pyrazinamide/rifampin
Note: Showing generic names only.
5
A
- abacavir
- abemaciclib
- abiraterone
- abrocitinib
- acalabrutinib
- acarbose
- acetaminophen
- acetohexamide
- acitretin
- acoramidis
- acrivastine
- adagrasib
- adalimumab
- ado-trastuzumab emtansine
- afatinib
- albiglutide
- albuterol
- aldesleukin
- alectinib
- alfentanil
- aliskiren
- allopurinol
- alogliptin
- alosetron
- alpelisib
- alprazolam
- aluminum carbonate
- aluminum hydroxide
- ambrisentan
- aminophylline
- aminosalicylic acid
- amiodarone
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amprenavir
- anagrelide
- anisindione
- apixaban
- apremilast
- aprepitant
- aprocitentan
- arformoterol
- aripiprazole
- armodafinil
- artesunate
- asciminib
- asenapine
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- atazanavir
- atezolizumab
- atogepant
- atomoxetine
- atorvastatin
- atovaquone
- atrasentan
- attapulgite
- auranofin
- aurothioglucose
- avacopan
- avanafil
- avapritinib
- avatrombopag
- avelumab
- axicabtagene ciloleucel
- axitinib
- azatadine
- azithromycin
B
- bcg
- bcg vaccine
- bedaquiline
- belinostat
- belumosudil
- belzutifan
- bempedoic acid
- benazepril
- bendamustine
- benznidazole
- bepridil
- berotralstat
- betamethasone
- betrixaban
- bexagliflozin
- bexarotene
- bicalutamide
- binimetinib
- bisoprolol
- bitolterol
- black cohosh
- blinatumomab
- boceprevir
- bortezomib
- bosentan
- bosutinib
- brentuximab
- brexpiprazole
- brexucabtagene autoleucel
- brigatinib
- brincidofovir
- brivaracetam
- bromfenac
- bromocriptine
- brompheniramine
- budesonide
- budesonide nasal
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabazitaxel
- cabotegravir
- cabozantinib
- calaspargase pegol
- calcifediol
- calcitriol
- calcium carbonate
- canagliflozin
- cannabidiol
- capivasertib
- capmatinib
- captopril
- carbamazepine
- carbinoxamine
- carboplatin
- carfilzomib
- cariprazine
- carmustine
- carvedilol
- caspofungin
- cefamandole
- cefazolin
- cefmetazole
- cefoperazone
- cefotetan
- ceftobiprole medocaril
- celecoxib
- cemiplimab
- ceritinib
- cerivastatin
- certolizumab
- cevimeline
- chaparral
- chenodiol
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- chlorcyclizine
- chlordiazepoxide
- chloroquine
- chlorotrianisene
- chlorpheniramine
- chlorpropamide
- chlorzoxazone
- cholecalciferol
- cholera vaccine, live
- cilostazol
- ciltacabtagene autoleucel
- cisplatin
- citalopram
- cladribine
- clarithromycin
- clavulanate
- clemastine
- clindamycin
- clobazam
- clofarabine
- clofibrate
- clomipramine
- clonazepam
- clopidogrel
- clorazepate
- clotrimazole
- clozapine
- cobicistat
- cobimetinib
- codeine
- colchicine
- comfrey
- conjugated estrogens
- conjugated estrogens topical
- copanlisib
- cortisone
- cosibelimab
- crinecerfont
- crizotinib
- cyclizine
- cyclobenzaprine
- cycloserine
- cyclosporine
- cyproheptadine
- cytarabine
D
- dabigatran
- dabrafenib
- dacarbazine
- daclatasvir
- daclizumab
- danazol
- danicopan
- dantrolene
- dapagliflozin
- daprodustat
- dapsone
- dapsone topical
- daridorexant
- darifenacin
- darolutamide
- darunavir
- dasatinib
- deferasirox
- deflazacort
- dehydroepiandrosterone
- delandistrogene moxeparvovec
- delavirdine
- demeclocycline
- deserpidine
- desipramine
- desvenlafaxine
- deucravacitinib
- dexamethasone
- dexbrompheniramine
- dexchlorpheniramine
- dexfenfluramine
- dexlansoprazole
- dextromethorphan
- diazepam
- diclofenac
- diclofenac topical
- dicumarol
- didanosine
- dienestrol topical
- diethylstilbestrol
- digitoxin
- digoxin
- dihydroergotamine
- dihydrotachysterol
- dihydroxyaluminum sodium carbonate
- diltiazem
- dimethyl fumarate
- dinutuximab
- diphenhydramine
- dipivefrin ophthalmic
- diroximel fumarate
- disopyramide
- disulfiram
- divalproex sodium
- dobutamine
- docetaxel
- dofetilide
- dolasetron
- dolutegravir
- donepezil
- doravirine
- dostarlimab
- doxepin
- doxepin topical
- doxercalciferol
- doxorubicin
- doxorubicin liposomal
- doxycycline
- dronedarone
- droperidol
- drospirenone
- droxidopa
- dulaglutide
- duloxetine
- durvalumab
- dutasteride
- duvelisib
E
- edoxaban
- efavirenz
- eflornithine
- elacestrant
- elafibranor
- elagolix
- eletriptan
- eliglustat
- elotuzumab
- elranatamab
- eltrombopag
- eluxadoline
- elvitegravir
- empagliflozin
- emtricitabine
- enalapril
- enalaprilat
- enasidenib
- encorafenib
- enflurane
- enfortumab vedotin
- enfuvirtide
- ensifentrine
- entrectinib
- enzalutamide
- ephedrine nasal
- epinephrine
- epinephrine ophthalmic
- epinephrine topical
- epirubicin
- eplerenone
- eravacycline
- erdafitinib
- ergocalciferol
- ergonovine
- ergotamine
- eribulin
- erlotinib
- ertugliflozin
- erythromycin
- escitalopram
- esomeprazole
- estazolam
- esterified estrogens
- estradiol
- estradiol topical
- estrone
- estropipate
- estropipate topical
- eszopiclone
- etanercept
- ethambutol
- ethanol
- ethinyl estradiol
- ethionamide
- ethotoin
- etodolac
- etonogestrel
- etoposide
- etranacogene dezaparvovec
- etrasimod
- etravirine
- etretinate
- everolimus
- exemestane
- exenatide
- ezetimibe
F
- febuxostat
- fecal microbiota spores, live
- fecal microbiota, live
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fenofibrate
- fenofibric acid
- fenoprofen
- fentanyl
- fesoterodine
- fexinidazole
- fexofenadine
- fezolinetant
- fidanacogene elaparvovec
- finerenone
- fitusiran
- flibanserin
- fluconazole
- fludarabine
- fludrocortisone
- fluoxetine
- fluoxymesterone
- flurazepam
- flurbiprofen
- flutamide
- fluvastatin
- fluvoxamine
- formoterol
- fosamprenavir
- fosaprepitant
- fosinopril
- fosphenytoin
- fostamatinib
- fostemsavir
- fruquintinib
- furazolidone
- futibatinib
G
- gadoxetate disodium
- ganaxolone
- gefitinib
- gemcitabine
- gemfibrozil
- gemtuzumab
- gepirone
- gilteritinib
- glasdegib
- glimepiride
- glipizide
- glofitamab
- glyburide
- gold sodium thiomalate
- golimumab
- grepafloxacin
- guanfacine
H
- halazepam
- halofantrine
- haloperidol
- halothane
- hemin
- hydralazine
- hydrocodone
- hydrocortisone
- hydroxychloroquine
- hydroxyprogesterone
- hydroxyzine
I
- ibrexafungerp
- ibrutinib
- ibuprofen
- idecabtagene vicleucel
- idelalisib
- imatinib
- imipramine
- indacaterol
- indinavir
- indium oxyquinoline in-111
- indomethacin
- infigratinib
- infliximab
- inotuzumab ozogamicin
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- interferon alfa-2a
- interferon alfa-2b
- interferon alfa-n1
- interferon alfacon-1
- interferon beta-1a
- interferon beta-1b
- interferon gamma-1b
- iodoquinol
- ipilimumab
- iptacopan
- irinotecan
- irinotecan liposomal
- isavuconazonium
- isocarboxazid
- isoetharine
- isoflurane
- isoproterenol
- isotretinoin
- isradipine
- istradefylline
- itraconazole
- ivabradine
- ivacaftor
- ivosidenib
- ixabepilone
- ixazomib
K
L
- labetalol
- lacosamide
- lamivudine
- lamotrigine
- lansoprazole
- lanthanum carbonate
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- lenacapavir
- lenalidomide
- leniolisib
- lenvatinib
- lesinurad
- letermovir
- levalbuterol
- levamlodipine
- levmetamfetamine nasal
- levobupivacaine
- levodopa
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levonorgestrel
- levothyroxine
- levothyroxine / liothyronine
- lidocaine
- linagliptin
- linezolid
- liothyronine
- liotrix
- liraglutide
- lisinopril
- lisocabtagene maraleucel
- lithium
- lixisenatide
- lomitapide
- lomustine
- lonafarnib
- lorlatinib
- losartan
- lovastatin
- lumateperone
- lurasidone
- lurbinectedin
M
- macimorelin
- macitentan
- magaldrate
- magnesium carbonate
- magnesium hydroxide
- maprotiline
- maralixibat
- maraviroc
- maribavir
- mavacamten
- mavorixafor
- meclofenamate
- medroxyprogesterone
- mefenamic acid
- mefloquine
- megestrol
- melatonin
- meloxicam
- meperidine
- mephenytoin
- mephobarbital
- mercaptopurine
- metaproterenol
- metaxalone
- metformin
- methadone
- methimazole
- methohexital
- methotrexate
- methoxamine
- methoxyflurane
- methyldopa
- methylene blue
- methylergonovine
- methylprednisolone
- methyltestosterone
- methysergide maleate
- metoclopramide
- metoprolol
- metronidazole
- mexiletine
- mibefradil
- midazolam
- midodrine
- midostaurin
- mifepristone
- miglitol
- milnacipran
- minocycline
- mipomersen
- mirabegron
- mirikizumab
- mirtazapine
- mirvetuximab soravtansine
- mitapivat
- mitotane
- mobocertinib
- modafinil
- moexipril
- momelotinib
- monomethyl fumarate
- montelukast
- morphine
- mosunetuzumab
- moxifloxacin
- mycophenolate mofetil
- mycophenolic acid
N
- nabumetone
- naldemedine
- naloxegol
- naltrexone
- nandrolone
- naphazoline nasal
- naphazoline ophthalmic
- naproxen
- natalizumab
- nateglinide
- naxitamab
- nefazodone
- nelarabine
- nelfinavir
- neratinib
- nevirapine
- niacin
- niacinamide
- nicardipine
- nicotinamide
- nifedipine
- nilotinib
- nilutamide
- nimodipine
- nintedanib
- nirogacestat
- nisoldipine
- nitisinone
- nitrofurantoin
- nivolumab
- norepinephrine
- norethindrone
- norgestrel
- nortriptyline
O
- obeticholic acid
- olanzapine
- olaparib
- oliceridine
- olodaterol
- olutasidenib
- omaveloxolone
- omeprazole
- onasemnogene abeparvovec
- ondansetron
- orlistat
- osilodrostat
- osimertinib
- ospemifene
- oxaliplatin
- oxandrolone
- oxaprozin
- oxcarbazepine
- oxtriphylline
- oxycodone
- oxymetazoline nasal
- oxymetazoline ophthalmic
- oxymetazoline topical
- oxymetholone
- oxytetracycline
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- paliperidone
- palovarotene
- panobinostat
- pantoprazole
- paricalcitol
- paroxetine
- pasireotide
- pazopanib
- pegaspargase
- peginterferon alfa-2a
- peginterferon alfa-2b
- peginterferon beta-1a
- pembrolizumab
- pemigatinib
- pemoline
- penbutolol
- pennyroyal
- pentobarbital
- perampanel
- perindopril
- pexidartinib
- phenazopyridine
- phenelzine
- phenindamine
- phenobarbital
- phenylbutazone
- phenylephrine nasal
- phenylephrine ophthalmic
- phenylephrine topical
- phenytoin
- pimavanserin
- pimecrolimus topical
- pimozide
- pioglitazone
- pirbuterol
- pirfenidone
- piroxicam
- pirtobrutinib
- pitavastatin
- pitolisant
- polatuzumab vedotin
- pomalidomide
- ponatinib
- ponesimod
- porfimer
- posaconazole
- pralatrexate
- pralsetinib
- pramlintide
- pravastatin
- praziquantel
- prednisolone
- prednisone
- pretomanid
- primidone
- probenecid
- procainamide
- procarbazine
- progesterone
- progesterone topical
- propafenone
- propofol
- propranolol
- propylhexedrine nasal
- propylthiouracil
- protriptyline
- pyrilamine
Q
R
- rabeprazole
- racepinephrine
- raltegravir
- ramelteon
- ramipril
- ranolazine
- rasagiline
- rauwolfia serpentina
- red yeast rice
- regorafenib
- relugolix
- remdesivir
- repaglinide
- repotrectinib
- reserpine
- resmetirom
- retapamulin topical
- retifanlimab
- revefenacin
- revumenib
- ribociclib
- rifabutin
- rifapentine
- rilpivirine
- riluzole
- rimegepant
- riociguat
- ripretinib
- risperidone
- ritlecitinib
- ritodrine
- ritonavir
- rivaroxaban
- rofecoxib
- roflumilast
- roflumilast topical
- rolapitant
- romidepsin
- ropeginterferon alfa-2b
- ropinirole
- ropivacaine
- rosiglitazone
- rosuvastatin
- rucaparib
- ruxolitinib
- ruxolitinib topical
S
- sacituzumab govitecan
- safinamide
- salmeterol
- saquinavir
- satralizumab
- saxagliptin
- secnidazole
- secobarbital
- seladelpar
- selegiline
- selexipag
- selinexor
- selpercatinib
- selumetinib
- semaglutide
- sertraline
- sibutramine
- sildenafil
- silodosin
- simeprevir
- simvastatin
- siponimod
- sirolimus
- sirolimus protein-bound
- sitagliptin
- sodium bicarbonate
- sofosbuvir
- solifenacin
- sonidegib
- sorafenib
- sotagliflozin
- sotorasib
- sparsentan
- st. john's wort
- stanozolol
- stavudine
- stiripentol
- sucralfate
- sufentanil
- sulfadiazine
- sulfadoxine
- sulfamethizole
- sulfamethoxazole
- sulfasalazine
- sulfinpyrazone
- sulfisoxazole
- sulindac
- sunitinib
- suvorexant
- suzetrigine
T
- tacrine
- tacrolimus
- tadalafil
- talquetamab
- tamoxifen
- tarlatamab
- tasimelteon
- tazemetostat
- teclistamab
- telaprevir
- telbivudine
- telithromycin
- temozolomide
- temsirolimus
- teniposide
- tenofovir alafenamide
- tenofovir disoproxil
- tepotinib
- terbinafine
- terbutaline
- teriflunomide
- testosterone
- testosterone topical
- tetracycline
- tetrahydrozoline nasal
- tetrahydrozoline ophthalmic
- thalidomide
- theophylline
- thioguanine
- thiopental
- thiotepa
- thiothixene
- thyroid desiccated
- ticagrelor
- timolol
- tinidazole
- tipranavir
- tirzepatide
- tisagenlecleucel
- tislelizumab
- tisotumab vedotin
- tivozanib
- tizanidine
- tocainide
- tocilizumab
- tofacitinib
- tolazamide
- tolbutamide
- tolcapone
- tolmetin
- tolterodine
- tolvaptan
- toremifene
- toripalimab
- torsemide
- tovorafenib
- trabectedin
- tramadol
- trandolapril
- tranylcypromine
- trazodone
- tremelimumab
- treprostinil
- tretinoin
- triamcinolone
- triamcinolone ophthalmic
- triazolam
- trimethoprim
- trimetrexate
- trimipramine
- tripelennamine
- triprolidine
- trofinetide
- troglitazone
- troleandomycin
- trovafloxacin
- tryptophan
- tucatinib
- typhoid vaccine, live
U
V
- vadadustat
- valbenazine
- valdecoxib
- valoctocogene roxaparvovec
- valproic acid
- valsartan
- vamorolone
- vandetanib
- vardenafil
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vilazodone
- vimseltinib
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- voclosporin
- vonoprazan
- vorapaxar
- vorasidenib
- voriconazole
- vortioxetine
- voxelotor
W
X
Y
Z
- zafirlukast
- zalcitabine
- zaleplon
- zanubrutinib
- zavegepant
- zidovudine
- zileuton
- ziprasidone
- zolbetuximab
- zolmitriptan
- zolpidem
- zonisamide
- zuranolone
Isoniazid/pyrazinamide/rifampin alcohol/food interactions
There are 2 alcohol/food interactions with isoniazid / pyrazinamide / rifampin.
Isoniazid/pyrazinamide/rifampin disease interactions
There are 17 disease interactions with isoniazid / pyrazinamide / rifampin which include:
- colitis
- hepatotoxicity
- liver disease
- peripheral neuropathy
- gout
- hepatotoxicity
- liver disease
- renal dysfunction
- hematopoietic disturbances
- hepatotoxicity
- liver disease
- porphyria
- hemodialysis
- renal dysfunction
- diabetes mellitus
- hemodialysis
- enzyme induction
Report options
QR code containing a link to this page
More about isoniazid / pyrazinamide / rifampin
- isoniazid/pyrazinamide/rifampin consumer information
- Check interactions
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: antituberculosis combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Levaquin
Levaquin (levofloxacin) is used to treat bronchitis, pneumonia, chlamydia, gonorrhea and skin ...
Reviews & ratings
Streptomycin
Streptomycin systemic is used for brucellosis, endocarditis, mycobacterium avium-intracellulare ...
Reviews & ratings
Featured
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Reviews & ratings
Ethambutol
Ethambutol systemic is used for mycobacterium avium-intracellulare, prophylaxis, mycobacterium ...
Reviews & ratings
Amikacin
Amikacin systemic is used for bacteremia, bone infection, cystic fibrosis, febrile neutropenia ...
Reviews & ratings
Isoniazid
Isoniazid systemic is used for mycobacterium kansasii, tuberculosis, active, tuberculosis, latent ...
Reviews & ratings
Moxifloxacin
Moxifloxacin systemic is used for anthrax, anthrax prophylaxis, bacterial infection, bronchitis ...
Reviews & ratings
Rifampin
Rifampin systemic is used for bartonellosis, endocarditis, haemophilus influenzae prophylaxis ...
Reviews & ratings
Levofloxacin
Levofloxacin is a fluoroquinolone antibiotic used to treat serious bacterial infections and prevent ...
Reviews & ratings
Ciprofloxacin
Ciprofloxacin is an antibiotic belong to a group of drugs called fluoroquinolones. Learn about side ...
Reviews & ratings
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
