Guaifenesin/phenylephrine/pyrilamine Interactions
There are 548 drugs known to interact with guaifenesin/phenylephrine/pyrilamine, along with 11 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 38 are major, 508 are moderate, and 2 are minor.
- View all 548 medications that may interact with guaifenesin/phenylephrine/pyrilamine
- View guaifenesin/phenylephrine/pyrilamine alcohol/food interactions (1)
- View guaifenesin/phenylephrine/pyrilamine disease interactions (11)
Most frequently checked interactions
View interaction reports for guaifenesin / phenylephrine / pyrilamine and the medicines listed below.
- Acetylsalicylic Acid (aspirin)
- Advil (ibuprofen)
- Advil Allergy Sinus (chlorpheniramine / ibuprofen / pseudoephedrine)
- Advil Cold and Sinus (ibuprofen / pseudoephedrine)
- Advil Migraine (ibuprofen)
- Advil PM (diphenhydramine / ibuprofen)
- Aleve (naproxen)
- Anacin (aspirin / caffeine)
- Anacin Advanced Headache Formula (acetaminophen / aspirin / caffeine)
- Anacin Aspirin Free (acetaminophen)
- Anacin Max Strength (aspirin / caffeine)
- Anacin PM Aspirin Free (acetaminophen / diphenhydramine)
- Apidra (insulin glulisine)
- Ascriptin (aspirin)
- Ascriptin Enteric (aspirin)
- Ascriptin Maximum Strength (aspirin)
- Caltrate 600 with Iron and Vitamin D (calcium / ferrous fumarate / vitamin d)
- Capzasin (capsaicin topical)
- Capzasin Back and Body (capsaicin topical)
- Capzasin-HP (capsaicin topical)
- Capzasin-HP Arthritis Formula (capsaicin topical)
- Capzasin-P (capsaicin topical)
- Centrum Silver Ultra Men's (multivitamin with minerals)
- Citracal Petites (calcium / vitamin d)
- Comtrex Acute Head Cold (acetaminophen / brompheniramine / pseudoephedrine)
- Comtrex Cold & Cough Day Night (acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine)
- Comtrex Cold and Flu Maximum Strength (acetaminophen / chlorpheniramine / dextromethorphan / phenylpropanolamine)
- Comtrex Cold and Flu Maximum Strength Liquid (acetaminophen / chlorpheniramine / dextromethorphan / pseudoephedrine)
- Comtrex Cold and Flu Maximum Strength Tablet (acetaminophen / chlorpheniramine / dextromethorphan / pseudoephedrine)
- Vitamin B12 (cyanocobalamin)
Guaifenesin/phenylephrine/pyrilamine alcohol/food interactions
There is 1 alcohol/food interaction with guaifenesin / phenylephrine / pyrilamine.
Guaifenesin/phenylephrine/pyrilamine disease interactions
There are 11 disease interactions with guaifenesin / phenylephrine / pyrilamine which include:
- depression
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- BPH
- diabetes
- glaucoma
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More about guaifenesin / phenylephrine / pyrilamine
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.