Guaifenesin / hydrocodone / phenylephrine Drug Interactions
A total of 602 drugs are known to interact with guaifenesin / hydrocodone / phenylephrine.
- 198 major drug interactions
- 402 moderate drug interactions
- 2 minor drug interactions
Check for interactions
Most frequently checked interactions
View interaction reports for guaifenesin / hydrocodone / phenylephrine and the medicines listed below.
- Acetylsalicylic Acid (aspirin)
- Advil (ibuprofen)
- Advil Allergy Sinus (chlorpheniramine / ibuprofen / pseudoephedrine)
- Advil Cold and Sinus (ibuprofen / pseudoephedrine)
- Advil Migraine (ibuprofen)
- Advil PM (diphenhydramine / ibuprofen)
- Aleve (naproxen)
- Anacin Advanced Headache Formula (acetaminophen / aspirin / caffeine)
- Ascriptin (aspirin)
- Ascriptin Enteric (aspirin)
- Ascriptin Maximum Strength (aspirin)
- Ecotrin (aspirin)
- Ecotrin Adult Low Strength (aspirin)
- Ecotrin Maximum Strength (aspirin)
- Excedrin (acetaminophen / aspirin / caffeine)
- Lasix (furosemide)
- Lopressor (metoprolol)
- Motrin (ibuprofen)
- Tylenol Extra Strength (acetaminophen)
- Vitamin B12 (cyanocobalamin)
Guaifenesin / hydrocodone / phenylephrine alcohol/food interactions
There is 1 alcohol/food interaction with guaifenesin / hydrocodone / phenylephrine
Guaifenesin / hydrocodone / phenylephrine disease interactions
There are 21 disease interactions with guaifenesin / hydrocodone / phenylephrine which include:
- impaired GI motility
- infectious diarrhea
- liver disease
- prematurity
- acute alcohol intoxication
- drug dependence
- gastrointestinal obstruction
- hypotension
- intracranial pressure
- respiratory depression
- cardiovascular disease
- adrenal insufficiency
- biliary spasm
- hypothyroidism
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- BPH
- diabetes
- glaucoma
More about guaifenesin/hydrocodone/phenylephrine
- Side Effects
- Dosage Information
- En Español
- Drug class: upper respiratory combinations
- FDA Alerts (2)
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
