Guaifenesin/hydrocodone/phenylephrine Interactions
There are 730 drugs known to interact with guaifenesin/hydrocodone/phenylephrine, along with 20 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 231 are major, 496 are moderate, and 3 are minor.
- View all 730 medications that may interact with guaifenesin/hydrocodone/phenylephrine
- View guaifenesin/hydrocodone/phenylephrine alcohol/food interactions (1)
- View guaifenesin/hydrocodone/phenylephrine disease interactions (20)
Most frequently checked interactions
View interaction reports for guaifenesin / hydrocodone / phenylephrine and the medicines listed below.
- Abilify (aripiprazole)
- Abilify (aripiprazole)
- Acetylsalicylic Acid (aspirin)
- Acetylsalicylic Acid (aspirin)
- Adderall (amphetamine / dextroamphetamine)
- Adderall (amphetamine / dextroamphetamine)
- Advil (ibuprofen)
- Advil (ibuprofen)
- Advil Allergy Sinus (chlorpheniramine / ibuprofen / pseudoephedrine)
- Advil Allergy Sinus (chlorpheniramine / ibuprofen / pseudoephedrine)
- Advil Cold and Sinus (ibuprofen / pseudoephedrine)
- Advil Cold and Sinus (ibuprofen / pseudoephedrine)
- Advil Migraine (ibuprofen)
- Advil Migraine (ibuprofen)
- Advil PM (diphenhydramine / ibuprofen)
- Advil PM (diphenhydramine / ibuprofen)
- Aleve (naproxen)
- Aleve (naproxen)
- Ambien (zolpidem)
- Ambien (zolpidem)
- Anacin (aspirin / caffeine)
- Anacin (aspirin / caffeine)
- Lasix (furosemide)
- Lasix (furosemide)
- Lopressor (metoprolol)
- Lopressor (metoprolol)
- Tylenol Extra Strength (acetaminophen)
- Tylenol Extra Strength (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
Guaifenesin/hydrocodone/phenylephrine alcohol/food interactions
There is 1 alcohol/food interaction with guaifenesin / hydrocodone / phenylephrine.
Guaifenesin/hydrocodone/phenylephrine disease interactions
There are 20 disease interactions with guaifenesin / hydrocodone / phenylephrine which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- BPH
- diabetes
- glaucoma
Report options
More about guaifenesin / hydrocodone / phenylephrine
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
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Mucinex D
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Ozempic
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Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Dextromethorphan/guaifenesin/phenylephrine
Dextromethorphan/guaifenesin/phenylephrine systemic is used for cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine systemic is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.