Skip to Content

Drug interactions between Benadryl and methylprednisolone

Results for the following 2 drugs:
Benadryl (diphenhydramine)
methylprednisolone

Interactions between your drugs

There were no interactions found in our database between Benadryl and methylprednisolone - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Benadryl

A total of 821 drugs (4853 brand and generic names) are known to interact with Benadryl.

methylprednisolone

A total of 764 drugs (3328 brand and generic names) are known to interact with methylprednisolone.

Drug and food interactions

Moderate

methylPREDNISolone food

Applies to: methylprednisolone

Grapefruit juice may increase the blood levels and effects of certain medications such as methylPREDNISolone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with methylPREDNISolone. However, if you have been regularly consuming grapefruit or grapefruit juice with methylPREDNISolone, do not alter the amounts of these products in your diet without first talking to your doctor or other healthcare professional. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

Switch to professional interaction data

Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide