Acetaminophen/guaifenesin/phenylephrine Interactions
There are 340 drugs known to interact with acetaminophen/guaifenesin/phenylephrine, along with 7 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 35 are major, 284 are moderate, and 21 are minor.
- View all 340 medications that may interact with acetaminophen/guaifenesin/phenylephrine
- View acetaminophen/guaifenesin/phenylephrine alcohol/food interactions (3)
- View acetaminophen/guaifenesin/phenylephrine disease interactions (7)
Most frequently checked interactions
View interaction reports for acetaminophen / guaifenesin / phenylephrine and the medicines listed below.
- Allegra (fexofenadine)
- Allegra (fexofenadine)
- Allegra-D 24 Hour Allergy & Congestion (fexofenadine / pseudoephedrine)
- Allegra-D 24 Hour Allergy & Congestion (fexofenadine / pseudoephedrine)
- Beano (alpha-d-galactosidase)
- Beano (alpha-d-galactosidase)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- Benadryl Allergy (diphenhydramine)
- Benadryl Allergy (diphenhydramine)
- Dramamine (dimenhydrinate)
- Dramamine (dimenhydrinate)
- Eliquis (apixaban)
- Eliquis (apixaban)
- EpiPen (epinephrine)
- EpiPen (epinephrine)
- Flexeril (cyclobenzaprine)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Flonase (fluticasone nasal)
- Flovent HFA (fluticasone)
- Flovent HFA (fluticasone)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Succinate ER (metoprolol)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Acetaminophen/guaifenesin/phenylephrine alcohol/food interactions
There are 3 alcohol/food interactions with acetaminophen / guaifenesin / phenylephrine.
Acetaminophen/guaifenesin/phenylephrine disease interactions
There are 7 disease interactions with acetaminophen / guaifenesin / phenylephrine which include:
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Promethazine VC with Codeine
Promethazine VC with Codeine is used for cough and nasal congestion
Mucinex D
Mucinex D (guaifenesin and pseudoephedrine) is used to treat nasal and sinus congestion, and to ...
Dupixent
Dupixent is used to treat eczema, eosinophilic or oral-corticosteroid-dependent asthma, chronic ...
Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
