Acetaminophen/codeine/guaifenesin/phenylephrine Interactions
There are 732 drugs known to interact with acetaminophen/codeine/guaifenesin/phenylephrine, along with 23 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 152 are major, 569 are moderate, and 11 are minor.
- View all 732 medications that may interact with acetaminophen/codeine/guaifenesin/phenylephrine
- View acetaminophen/codeine/guaifenesin/phenylephrine alcohol/food interactions (3)
- View acetaminophen/codeine/guaifenesin/phenylephrine disease interactions (23)
Most frequently checked interactions
View interaction reports for acetaminophen / codeine / guaifenesin / phenylephrine and the medicines listed below.
- Advil (ibuprofen)
- Afrin (oxymetazoline nasal)
- Celexa (citalopram)
- Cheratussin AC (codeine / guaifenesin)
- Keppra (levetiracetam)
- Lactaid (lactase)
- Levothroid (levothyroxine)
- Lortab (acetaminophen / hydrocodone)
- Mag-Ox 400 (magnesium oxide)
- MethylPREDNISolone Dose Pack (methylprednisolone)
- Plaquenil (hydroxychloroquine)
- Prilosec OTC (omeprazole)
- ProAir HFA (albuterol)
- Tibsovo (ivosidenib)
- Tylenol (acetaminophen)
- Tylenol Arthritis Pain (acetaminophen)
Acetaminophen/codeine/guaifenesin/phenylephrine alcohol/food interactions
There are 3 alcohol/food interactions with acetaminophen / codeine / guaifenesin / phenylephrine.
Acetaminophen/codeine/guaifenesin/phenylephrine disease interactions
There are 23 disease interactions with acetaminophen / codeine / guaifenesin / phenylephrine which include:
- alcoholism
- liver disease
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- PKU
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- BPH
- diabetes
- glaucoma
Report options
More about acetaminophen / codeine / guaifenesin / phenylephrine
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.