Acetaminophen/codeine/guaifenesin/phenylephrine Interactions
There are 731 drugs known to interact with acetaminophen/codeine/guaifenesin/phenylephrine, along with 23 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 151 are major, 569 are moderate, and 11 are minor.
- View all 731 medications that may interact with acetaminophen/codeine/guaifenesin/phenylephrine
- View acetaminophen/codeine/guaifenesin/phenylephrine alcohol/food interactions (3)
- View acetaminophen/codeine/guaifenesin/phenylephrine disease interactions (23)
Most frequently checked interactions
View interaction reports for acetaminophen / codeine / guaifenesin / phenylephrine and the medicines listed below.
- Advil (ibuprofen)
- Afrin (oxymetazoline nasal)
- Celexa (citalopram)
- Cheratussin AC (codeine / guaifenesin)
- Keppra (levetiracetam)
- Lactaid (lactase)
- Levothroid (levothyroxine)
- Lortab (acetaminophen / hydrocodone)
- Mag-Ox 400 (magnesium oxide)
- MethylPREDNISolone Dose Pack (methylprednisolone)
- Plaquenil (hydroxychloroquine)
- Prilosec OTC (omeprazole)
- ProAir HFA (albuterol)
- Tibsovo (ivosidenib)
- Tylenol (acetaminophen)
- Tylenol Arthritis Pain (acetaminophen)
Acetaminophen/codeine/guaifenesin/phenylephrine alcohol/food interactions
There are 3 alcohol/food interactions with acetaminophen / codeine / guaifenesin / phenylephrine.
Acetaminophen/codeine/guaifenesin/phenylephrine disease interactions
There are 23 disease interactions with acetaminophen / codeine / guaifenesin / phenylephrine which include:
- alcoholism
- liver disease
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- PKU
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- BPH
- diabetes
- glaucoma
Report options
More about acetaminophen / codeine / guaifenesin / phenylephrine
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Promethazine VC with Codeine
Promethazine VC with Codeine is used for cough and nasal congestion
Mucinex D
Mucinex D (guaifenesin and pseudoephedrine) is used to treat nasal and sinus congestion, and to ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Vicks Nyquil Cough
Vicks Nyquil Cough is used for cough, cough and nasal congestion
Dextromethorphan/guaifenesin/phenylephrine
Dextromethorphan/guaifenesin/phenylephrine systemic is used for cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine systemic is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.