Acetaminophen/chlorpheniramine/phenylephrine Interactions
There are 603 drugs known to interact with acetaminophen/chlorpheniramine/phenylephrine, along with 11 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 46 are major, 542 are moderate, and 15 are minor.
- View all 603 medications that may interact with acetaminophen/chlorpheniramine/phenylephrine
- View acetaminophen/chlorpheniramine/phenylephrine alcohol/food interactions (1)
- View acetaminophen/chlorpheniramine/phenylephrine disease interactions (11)
Most frequently checked interactions
View interaction reports for acetaminophen / chlorpheniramine / phenylephrine and the medicines listed below.
- Alcohol (contained in alcoholic beverages) (ethanol)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Aleve (naproxen)
- Aleve (naproxen)
- Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate)
- Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate)
- Alka-Seltzer Plus Maximum Strength Day & Night Cold & Flu Liquid Gels (Night Formula) (acetaminophen / dextromethorphan / doxylamine / phenylephrine)
- Alka-Seltzer Plus Maximum Strength Day & Night Cold & Flu Liquid Gels (Night Formula) (acetaminophen / dextromethorphan / doxylamine / phenylephrine)
- Allegra (fexofenadine)
- Allegra (fexofenadine)
- Augmentin (amoxicillin / clavulanate)
- Augmentin (amoxicillin / clavulanate)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- Excedrin PM Headache (acetaminophen / aspirin / diphenhydramine)
- Excedrin PM Headache (acetaminophen / aspirin / diphenhydramine)
- Flonase (fluticasone nasal)
- Flonase (fluticasone nasal)
- Tylenol (acetaminophen)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Wellbutrin XL (bupropion)
- Wellbutrin XL (bupropion)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Acetaminophen/chlorpheniramine/phenylephrine alcohol/food interactions
There is 1 alcohol/food interaction with acetaminophen / chlorpheniramine / phenylephrine.
Acetaminophen/chlorpheniramine/phenylephrine disease interactions
There are 11 disease interactions with acetaminophen / chlorpheniramine / phenylephrine which include:
- alcoholism
- liver disease
- cardiovascular disease
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- BPH
- diabetes
- glaucoma
Report options
More about acetaminophen / chlorpheniramine / phenylephrine
- acetaminophen/chlorpheniramine/phenylephrine consumer information
- Compare alternatives
- Reviews (21)
- Drug images
- Side effects
- Dosage information
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
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Ozempic
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Conex
Conex is used for allergic rhinitis, cold symptoms, nasal congestion, sinus symptoms
Alka-Seltzer Plus Cold
Alka-Seltzer Plus Cold is used for cold symptoms, sinus symptoms
Guaifenesin/phenylephrine
Guaifenesin/phenylephrine is used for cough and nasal congestion, sinus symptoms
Acetaminophen/dextromethorphan/phenylephrine
Acetaminophen/dextromethorphan/phenylephrine is used for cold symptoms, cough, cough and nasal ...
Naproxen/pseudoephedrine
Naproxen/pseudoephedrine is used for nasal congestion, pain/fever, sinus symptoms
Ibuprofen/pseudoephedrine
Ibuprofen/pseudoephedrine is used for sinus symptoms
Mometasone nasal
Mometasone nasal is used for allergic rhinitis, allergies, nasal polyps, sinus symptoms
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
