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VEGF/VEGFR inhibitors

What are VEGF/VEGFR inhibitors

Vascular endothelial growth factor (VEGF)/ vascular endothelial growth factor receptor (VEGFR) inhibitors are agents that inhibit the activity of VEGF and VEGFR. VEGR and VEGFR (a tyrosine kinase receptor) signaling modulates angiogenesis, which involves making of new blood vessels from existing blood vessels.

Abnormal angiogenesis is known to occur in cancer, degenerative eye conditions and other conditions that involve inflammation. Specific monoclonal antibodies can be used as VEGF inhibitors and particular tyrosine kinase inhibitors are used as VEGFR inhibitors.

Vascular endothelial growth factor (VEGF)/ vascular endothelial growth factor receptor (VEGFR) inhibitors are used to treat various types of cancers.

List of VEGF/VEGFR inhibitors:

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Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
pazopanib systemic (Pro, More...)
58 reviews
   
8.5
bevacizumab systemic (Pro, More...)
22 reviews
   
8.4
sunitinib systemic (Pro, More...)
19 reviews
   
7.4
sorafenib systemic (Pro, More...)
10 reviews
   
6.9
axitinib systemic (Pro, More...)
0 reviews
   
6.0
ponatinib systemic (Pro, More...)
2 reviews
   
3.0
cabozantinib systemic (Pro, More...)
1 review
   
1.0
regorafenib systemic (Pro, More...)
2 reviews
   
1.0
lenvatinib systemic (Pro, More...)
0 reviews
   
0.0
ramucirumab systemic (Pro, More...)
0 reviews
   
0.0
vandetanib systemic (Pro, More...)
0 reviews
   
0.0
ziv-aflibercept systemic (Pro, More...)
0 reviews
   
0.0
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