Ziextenzo Dosage
Generic name: PEGFILGRASTIM 6mg in 0.6mL
Dosage form: injection
Drug class: Colony stimulating factors
Medically reviewed by Drugs.com. Last updated on Dec 4, 2024.
Patients with Cancer Receiving Myelosuppressive Chemotherapy
The recommended dosage of ZIEXTENZO is a single subcutaneous injection of 6 mg administered once per chemotherapy cycle. For dosing in pediatric patients weighing less than 45 kg, refer to Table 1. Do not administer ZIEXTENZO between 14 days before and 24 hours after administration of cytotoxic chemotherapy.
Administration
ZIEXTENZO is administered subcutaneously via a single-dose prefilled syringe for manual use.
Prior to use‚ remove the carton from the refrigerator and allow the ZIEXTENZO prefilled syringe to reach room temperature for a minimum of 15-30 minutes. Discard any prefilled syringe left at room temperature for greater than 120 hours.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. ZIEXTENZO is supplied as a clear and colorless to slightly yellowish solution. Do not administer ZIEXTENZO if discoloration or particulates are observed.
The ZIEXTENZO syringe plunger stopper and needle cap are not made with natural rubber latex.
Pediatric Patients weighing less than 45 kg
The ZIEXTENZO prefilled syringe is not designed to allow for direct administration of doses less than 0.6 mL (6 mg). The syringe does not bear graduation marks, which are necessary to accurately measure doses of ZIEXTENZO less than 0.6 mL (6 mg) for direct administration to patients. Thus, the direct administration to patients requiring dosing of less than 0.6 mL (6 mg) is not recommended due to the potential for dosing errors. Refer to Table 1.
|
||
Body Weight |
ZIEXTENZO Dose |
Volume to Administer |
Less than 10 kg* |
See below* |
See below* |
10 - 20 kg |
1.5 mg |
0.15 mL |
21 - 30 kg |
2.5 mg |
0.25 mL |
31 - 44 kg |
4 mg |
0.4 mL |
Frequently asked questions
- What are biosimilar drugs and how do they compare to biologics?
- What does cbqv stand for in pegfilgrastim?
- What biosimilars have been approved in the United States?
- What is the difference between Fulphila and Neulasta?
- What is the difference between Udenyca and Neulasta?
- How is Fulphila injected / administered?
- Is Fulphila a chemo drug?
- What is the difference between Udenyca and Fulphila?
More about Ziextenzo (pegfilgrastim)
- Check interactions
- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- During pregnancy
- FDA approval history
- Drug class: colony stimulating factors
- En español
Patient resources
- Ziextenzo drug information
- ZIEXTENZO (Pegfilgrastim Subcutaneous) (Advanced Reading)
- ZIEXTENZO (Pegfilgrastim-bmez Subcutaneous) (Advanced Reading)
Other brands
Neulasta, Fulphila, Udenyca, Nyvepria, ... +2 more
Professional resources
Other brands
Neulasta, Fulphila, Udenyca, Nyvepria, ... +2 more
Related treatment guides
See also:
Neulasta
Neulasta is used to stimulate neutrophil growth and reduce infection risk (manifested by febrile ...
Zarxio
Zarxio (filgrastim-sndz) is biosimilar product used to treat neutropenia associated with ...
Botox
Botox is used cosmetically to reduce facial lines and wrinkles and for medical purposes for ...
Neupogen
Neupogen (filgrastim) is used to treat neutropenia, a lack of certain white blood cells caused by ...
Fulphila
Fulphila is used for febrile neutropenia, neutropenia associated with chemotherapy
Udenyca
Udenyca is used for febrile neutropenia, hematopoietic syndrome of acute radiation syndrome ...
Nivestym
Nivestym is used for bone marrow transplantation, neutropenia, neutropenia associated with ...
Releuko
Releuko is used for bone marrow transplantation, neutropenia, neutropenia associated with chemotherapy
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.