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Symjepi Injection Dosage

Generic name: epinephrine 0.3mg in 0.3mL
Dosage form: injection
Drug classes: Adrenergic bronchodilators, Catecholamines, Vasopressors

Medically reviewed by Last updated on Nov 30, 2023.

Recommended Dosage According to Patient Body Weight

  • Patients greater than or equal to 30 kg (approximately 66 pounds or more): 0.3 mg
  • Patients 15 kg to 30 kg (33 pounds to 66 pounds): 0.15 mg.

Administration Instructions

  • Inject the single-dose SYMJEPI intramuscularly or subcutaneously into the anterolateral aspect of the thigh with the needle facing downwards. It can be injected through clothing if necessary. Do not inject intravenously, and do not inject into buttocks, into digits, hands and feet [see Warnings and Precautions (5.2)].
  • Instruct caregivers of young children who are prescribed SYMJEPI and who may be uncooperative and kick or move during an injection to hold the leg firmly in place and limit movement prior to and during an injection [see Warnings and Precautions (5.2)].
  • Each SYMJEPI is a single dose of epinephrine injection for single use. Since the doses of epinephrine delivered from SYMJEPI are fixed, consider using other forms of injectable epinephrine if doses lower than 0.15 mg are deemed necessary.
  • With severe persistent anaphylaxis, repeat injections with an additional SYMJEPI may be necessary. More than two sequential doses of epinephrine should only be administered under direct medical supervision [see Warnings and Precautions (5.1)].
  • Ensure that the patient or caregiver is instructed and understands the indications and use of this product. A health care provider should review the patient instructions for SYMJEPI, in detail, with the patient or caregiver. Patients and/or any other person who might be in a position to administer an epinephrine injection should be advised of the proper site for injection and given appropriate instructions about imbedding the needle before transferring the thumb to the syringe plunger [see Instructions for Use].
  • The epinephrine solution in the syringe should be inspected visually for particulate matter and discoloration.

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.