Secnidazole Dosage

Medically reviewed by Drugs.com. Last updated on May 5, 2023.

Usual Adult Dose for Bacterial Vaginosis

2 g orally once

Use: For the treatment of bacterial vaginosis in female patients

Usual Adult Dose for Trichomoniasis

2 g orally once

Comments:

• Sexual partners of infected patients should be treated with the same dose at the same time to prevent reinfection as trichomoniasis is a sexually transmitted disease with potentially serious sequelae.

Use: For the treatment of trichomoniasis due to Trichomonas vaginalis

Usual Pediatric Dose for Bacterial Vaginosis

12 years or older: 2 g orally once

Use: For the treatment of bacterial vaginosis in female patients

Usual Pediatric Dose for Trichomoniasis

12 years or older: 2 g orally once

Comments:

• Sexual partners of infected patients should be treated with the same dose at the same time to prevent reinfection as trichomoniasis is a sexually transmitted disease with potentially serious sequelae.

Use: For the treatment of trichomoniasis due to T vaginalis

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Known hypersensitivity to the active component or other nitroimidazole derivatives
• Cockayne syndrome

Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Administer a single packet of granules; sprinkle the entire contents of the packet onto applesauce, yogurt, or pudding.
• Consume the entire mixture of food and granules within 30 minutes of preparation; do not chew or crunch the granules.
• May administer without regard to the timing of meals
• After consuming this drug, may drink a glass of water (to help with swallowing)

Reconstitution/preparation techniques:

• The entire contents of 1 packet should be sprinkled onto applesauce, yogurt, or pudding; the granules will not dissolve.
• The granules are not intended to be dissolved in any liquid.

General:

• A single packet of granules contains 2 g of this drug.
• To reduce the development of drug-resistant organisms and maintain effective therapy, this drug should be used only to treat or prevent infections proven or strongly suspected to be caused by susceptible bacteria.
• Culture and susceptibility information should be considered when selecting/modifying antibacterial therapy or, if no data are available, local epidemiology and susceptibility patterns may be considered when selecting empiric therapy.

Patient advice:

• Read the US FDA-approved patient labeling (Patient Information and Instructions for Use).
• Do not consume alcoholic beverages or products containing ethanol or propylene glycol during treatment and for at least 48 hours after completing therapy; nausea, vomiting, diarrhea, abdominal pain, dizziness, and headache may occur.
• Do not breastfeed during treatment or for 96 hours after dose administration.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer