Sacrosidase Dosage

Medically reviewed by Drugs.com. Last updated on Sep 26, 2024.

Usual Adult Dose for Sucrase-Isomaltase Deficiency

Up to 15 kg: 1 mL (8500 international units) OR 1 full measuring scoop OR 28 drops orally per meal or snack
Over 15 kg: 2 mL (17,000 international units) OR 2 full measuring scoops OR 56 drops orally per meal or snack

Comment: Half the dose should be administered at beginning of meal or snack and the remainder during the meal or snack.

Use: Oral replacement therapy of genetically determined sucrase deficiency in patients with congenital sucrase-isomaltase deficiency (CSID)

Usual Pediatric Dose for Sucrase-Isomaltase Deficiency

5 months and older:

• Up to 15 kg: 1 mL (8500 international units) OR 1 full measuring scoop OR 28 drops orally per meal or snack
• Over 15 kg: 2 mL (17,000 international units) OR 2 full measuring scoops OR 56 drops orally per meal or snack

Comment: Half the dose should be administered at beginning of meal or snack and the remainder during the meal or snack.

Use: Oral replacement therapy of genetically determined sucrase deficiency in patients with CSID

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS: Hypersensitivity to the active component, yeast, yeast products, glycerin (glycerol), papain, or to any of the ingredients

Safety and efficacy have not been established in patients younger than 5 months.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Rinse the measuring scoop with water after each use.
• Do not add to warm or hot liquids; patients should not heat solutions containing this drug.
• Do not reconstitute or consume with fruit juice.
• This drug is fully soluble with infant formula, milk, and water.

Storage requirements:

• Discard 4 weeks after opening due to the potential for bacterial growth.
• Store in a refrigerator at 2C to 8C (36F to 46F).

General:

• This drug is sensitive to heat.
• This drug may contain small amounts of papain, which could result in allergic reactions.

Patient advice:

• Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
• Patients should be instructed to seek medical attention in the event of a hypersensitivity reaction.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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