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Medications for Sucrase-Isomaltase Deficiency

About Sucrase-Isomaltase Deficiency: 

Sucrase-Isomaltase deficiency is when the body does not make enough, or any, of the enzyme sucrase-isomaltase. This enzyme breaks down these carbohydrates in our food, sucrose (sugar), starch, and isomaltose into smaller units of glucose and fructose which we then use to make energy.

If you have a sucrase-isomaltase deficiency then you will be unable to break these carbohydrates down to smaller units so you can digest them. This means you will not be able to absorb energy out of the food, which can result in low blood sugar levels, poor weight gain and growth.  As these carbohydrates pass right through the digestive tract without being broken down, they can cause symptoms of abdominal cramps, bloating, diarrhea, constipation, excessive gas production, and vomiting.


Causes of Sucrase-Isomaltase Deficiency

Sucrase-isomaltase deficiency can be due genetic mutations where you do not have the correct genetic code to make the enzyme.
Intolerance develops when there is a reduction in levels of sucrase-isomaltase which can be caused by aging, small intestinal disease, or irritable bowel syndrome.

Drugs Used to Treat Sucrase-Isomaltase Deficiency

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
sacrosidase C N Add review Rate

Generic name: sacrosidase systemic

Brand name:  Sucraid

Drug class: digestive enzymes

For consumers: dosage,

For professionals: AHFS DI Monograph

Sucraid C N Add review Rate

Generic name: sacrosidase systemic

Drug class: digestive enzymes

For consumers: dosage, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Learn more about Sucrase-Isomaltase Deficiency

IBM Watson Micromedex

Legend

Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Off Label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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