Generic name: MEASLES VIRUS STRAIN ENDERS' ATTENUATED EDMONSTON LIVE ANTIGEN 1000[TCID_50] in 0.5mL, MUMPS VIRUS STRAIN B LEVEL JERYL LYNN LIVE ANTIGEN 20000[TCID_50] in 0.5mL, RUBELLA VIRUS STRAIN WISTAR RA 27/3 LIVE ANTIGEN 1000[TCID_50] in 0.5mL, VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN 9772[PFU] in 0.5mL
Dosage form: subcutaneous injection, powder, lyophilized, for suspension
Drug class: Vaccine combinations
Medically reviewed by Drugs.com. Last updated on Apr 13, 2021.
FOR SUBCUTANEOUS ADMINISTRATION ONLY
Recommended Dose and Schedule
Each 0.5-mL dose of ProQuad is administered subcutaneously.
The first dose is administered at 12 to 15 months of age but may be given anytime through 12 years of age.
The second dose is administered at 4 to 6 years of age. At least 1 month should elapse between a dose of a measles-containing vaccine and a dose of ProQuad. At least 3 months should elapse between a dose of varicella-containing vaccine and ProQuad.
Preparation for Administration
Use a sterile syringe free of preservatives, antiseptics, and detergents for each injection and/or reconstitution of the vaccine because these substances may inactivate the live virus vaccine. To reconstitute, use only the diluent supplied with the vaccine since it is free of preservatives or other antiviral substances which might inactivate the vaccine.
To reconstitute the vaccine, withdraw the entire volume of the supplied diluent from its vial and inject into lyophilized vaccine vial. Agitate to dissolve completely. Discard if the lyophilized vaccine cannot be dissolved.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Visually inspect the vaccine before and after reconstitution prior to administration. Do not use the product if particulates are present or if it appears discolored. Before reconstitution, the lyophilized vaccine is a white to pale yellow compact crystalline plug. ProQuad, when reconstituted, is a clear pale yellow to light pink liquid.
Withdraw the entire amount of the reconstituted vaccine from the vial into the same syringe, inject the entire volume, and discard vial.
To minimize loss of potency, the vaccine should be administered immediately after reconstitution. If not used immediately, the reconstituted vaccine may be stored at room temperature, protected from light, for up to 30 minutes. Discard reconstituted vaccine if it is not used within 30 minutes.
More about ProQuad (measles virus vaccine / mumps virus vaccine / rubella virus vaccine / varicella virus vaccine)
- Side effects
- Drug interactions
- During pregnancy
- Pricing & coupons
- En español
- Drug class: vaccine combinations
- FDA approval history
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