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Peginterferon Beta-1A Dosage

Applies to the following strength(s): 125 mcg/0.5 mL

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Multiple Sclerosis

Initial dose: 63 mcg injected subcutaneously on day 1, 94 mcg on day 15 (14 days later), reaching the full dose of 125 mcg on day 29 (after another 14 days)
Maintenance dose:125 mcg injected subcutaneously every 14 days

Comments:
-Patient should be advised to rotate sites for subcutaneous injections. The usual sites for subcutaneous injections are abdomen, back of the upper arm, and thigh.
-Prophylactic and concurrent use of analgesics and/or antipyretics may prevent or reduce flu-like symptoms sometimes experienced during treatment.

Renal Dose Adjustments

Dose adjustment(s) may be required; however, no specific guidelines have been suggested. Caution is recommended.

Liver Dose Adjustments

Dose adjustment(s) may be required; however, no specific guidelines have been suggested. Caution is recommended.

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Dose adjustment(s) may be required; however, no specific guidelines have been suggested.

Other Comments

Storage requirements:
-Store in a refrigerator between 2C to 8C (36F to 46F).
-Do not freeze.
-Allow drug to warm to room temperature (about 30 minutes) prior to use.
-Store in the closed original carton to protect from light.

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