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Methoxsalen Dosage

Medically reviewed by Drugs.com. Last updated on Aug 7, 2023.

Applies to the following strengths: 10 mg; 20 mcg/mL

Usual Adult Dose for Psoriasis

**Soft Gelatin Capsules are NOT interchangeable with other dosage forms. The manufacturer product information should be consulted.**

Soft gelatin capsules:

Initial dose: Take capsules orally 1.5 to 2 hours before UVA exposure with some low fat food or milk according to patient weight:
Weight : soft gelatin capsule dose
Under 30 kg: 10 mg
30 to 50 kg: 20 mg
51 to 65 kg: 30 mg
66 to 80 kg: 40 mg
81 to 90 kg: 50 mg
91 to 115 kg: 60 kg
Over 115 kg: 70 mg


Maintenance dose: Dose, schedule, and UVA exposure are based on the patients skin type, grades of erythema, and response to therapy per guidelines in professional literature.

Comments:

Use(s): Symptomatic control of severe, recalcitrant, disabling psoriasis not adequately responsive to other forms of therapy and when the diagnosis has been supported by biopsy.

Usual Adult Dose for Cutaneous T-cell Lymphoma

Extracorporeal administration:


Treatment volume x 0.017 = mL of Uvadex(R) for each treatment

Normal treatment schedule: Treatment is given on 2 consecutive days every 4 weeks for a minimum of 7 treatment cycles (6 months)

Accelerated treatment schedule: If patient assessment during the 4th treatment cycle (about 3 months) shows an increased skin score from baseline, treatment frequency may be increased to 2 consecutive treatments every 2 weeks.

Duration of therapy: 6 months

Comments:

Use(s): Palliative treatment of skin manifestations of cutaneous T-cell lymphoma that is unresponsive to other forms of treatment.

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

Use with caution.

Dose Adjustments

Precautions

US BOXED WARNING(S):

Recommendations:


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.